Pyridine, 3-[1-[(trimethylsilyl)oxy]ethenyl]-

Base Information

• Chemical Name: Pyridine, 3-[1-[(trimethylsilyl)oxy]ethenyl]-
• CAS No.: 104501-58-8
• Molecular Formula: C10H15NOSi
• Molecular Weight: 193.321
• DSSTox Substance ID: DTXSID30542009
• Nikkaji Number: J781.855F
• Wikidata: Q82418514
• Mol file: 104501-58-8.mol

Synonyms:104501-58-8;trimethyl(1-pyridin-3-ylethenoxy)silane;Pyridine, 3-[1-[(trimethylsilyl)oxy]ethenyl]-;1-Trimethylsilyloxy-1-(3-pyridyl)-ethene;DTXSID30542009;3-{1-[(Trimethylsilyl)oxy]ethenyl}pyridine

Chemical Property of Pyridine, 3-[1-[(trimethylsilyl)oxy]ethenyl]-

Chemical Property:

• PSA: 22.12000
• LogP: 2.90380
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 193.092290636
• Heavy Atom Count: 13
• Complexity: 186

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)OC(=C)C1=CN=CC=C1

Technology Process of Pyridine, 3-[1-[(trimethylsilyl)oxy]ethenyl]-

There total 2 articles about Pyridine, 3-[1-[(trimethylsilyl)oxy]ethenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl-3-pyridylketone (350-03-8) + trimethylsilyl trifluoromethanesulfonate (27607-77-8) → 1-Trimethylsilyloxy-1-(3-pyridyl)-ethene (104501-58-8)

Guidance literature:

With triethylamine; In benzene; for 3h; Heating;

DOI:10.1002/ardp.19883210314

Reference yield: 72.0%

methyl-3-pyridylketone (350-03-8) + chloro-trimethyl-silane (75-77-4) → 1-Trimethylsilyloxy-1-(3-pyridyl)-ethene (104501-58-8)

Guidance literature:

With triethylamine; sodium iodide; In acetonitrile; at 20 ℃; Inert atmosphere;

DOI:10.1039/d1cc06529g

Reference yield: 38.0%

1-Trimethylsilyloxy-1-(3-pyridyl)-ethene (104501-58-8) → 3-Hydroxyacetylpyridine (104501-59-9)

Guidance literature:

With iodosylbenzene; boron trifluoride diethyl etherate; water; In dichloromethane; 1.) -40 deg C, 1 h, 2.) room temp., 30 min;

DOI:10.1055/s-1985-31394

upstream raw materials:

methyl-3-pyridylketone

trimethylsilyl trifluoromethanesulfonate

chloro-trimethyl-silane

Downstream raw materials:

3-Hydroxyacetylpyridine

Myosmine

N,N-dimethyl-3-oxo-(3-pyridinyl)-1-propanamine hydrochloride

4-oxo-4-(pyridin-3-yl)butanenitrile