n-(2-Anilino-2-oxoethyl)benzamide

Base Information

• Chemical Name: n-(2-Anilino-2-oxoethyl)benzamide
• CAS No.: 3106-11-4
• Molecular Formula: C15H14 N2 O2
• Molecular Weight: 254.288
• NSC Number: 111074
• DSSTox Substance ID: DTXSID90296697
• Nikkaji Number: J807.296E
• Wikidata: Q82037406
• ChEMBL ID: CHEMBL2299181
• Mol file: 3106-11-4.mol

Synonyms:n-(2-anilino-2-oxoethyl)benzamide;3106-11-4;Hippuranilide;Hippursaureanilid;NSC111074;SCHEMBL3050069;CHEMBL2299181;DTXSID90296697;HMS1599K18;STL255152;AKOS001461669;NSC-111074;N-[2-oxo-2-(phenylamino)ethyl]benzamide;N~1~-(2-ANILINO-2-OXOETHYL)BENZAMIDE;SR-01000287041;SR-01000287041-1;Z31504389

Chemical Property of n-(2-Anilino-2-oxoethyl)benzamide

Chemical Property:

• Vapor Pressure: 1E-12mmHg at 25°C
• Boiling Point: 563.6°C at 760 mmHg
• Flash Point: 232.7°C
• Density: 1.226g/cm³
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 254.105527694
• Heavy Atom Count: 19
• Complexity: 305

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NCC(=O)NC2=CC=CC=C2

Technology Process of n-(2-Anilino-2-oxoethyl)benzamide

There total 29 articles about n-(2-Anilino-2-oxoethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-amino-N-phenyl-acetamide (555-48-6) + benzoyl chloride (98-88-4) → hippurylanilide (3106-11-4)

Guidance literature:

With potassium carbonate; In chloroform; for 4h;

Reference yield: 79.0%

4-anilinomethylene-2-phenyl-2-oxazoline-5-one → hippurylanilide (3106-11-4)

Guidance literature:

With sodium methylate; In methanol; for 3h; Heating;

Reference yield: 75.0%

Hippuric Acid (495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2) + aniline (62-53-3) → hippurylanilide (3106-11-4)

Guidance literature:

With triethylamine; fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2.5h;

DOI:10.1080/00304940309355842

upstream raw materials:

Hippuric Acid

anthranilic acid

aniline

diethyl ether

Downstream raw materials:

4-( N,N-dimethylaminomethylene)-2-phenyl-2-oxazolin-5-one

5-chloro-1,2-diphenyl-1H-imidazole