Benzenemethanamine, N-[3-chloro-2-[(trimethylsilyl)oxy]propyl]-

Base Information

Chemical Name:Benzenemethanamine, N-[3-chloro-2-[(trimethylsilyl)oxy]propyl]-
CAS No.:111043-32-4
Molecular Formula:C13H22ClNOSi
Molecular Weight:271.862
Hs Code.:
DSSTox Substance ID:DTXSID90431884
Mol file:111043-32-4.mol

Synonyms:111043-32-4;N-Benzyl-3-chloro-2-((trimethylsilyl)oxy)propan-1-amine;Benzenemethanamine, N-[3-chloro-2-[(trimethylsilyl)oxy]propyl]-;SCHEMBL2920578;DTXSID90431884

Suppliers and Price of Benzenemethanamine, N-[3-chloro-2-[(trimethylsilyl)oxy]propyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Benzenemethanamine, N-[3-chloro-2-[(trimethylsilyl)oxy]propyl]-

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:271.1159186
Heavy Atom Count:17
Complexity:202

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)OC(CNCC1=CC=CC=C1)CCl

Technology Process of Benzenemethanamine, N-[3-chloro-2-[(trimethylsilyl)oxy]propyl]-

There total 5 articles about Benzenemethanamine, N-[3-chloro-2-[(trimethylsilyl)oxy]propyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 75605-52-6,278788-93-5
N-benzyl-3-amino-1-chloropropan-2-ol

: 13435-12-6
N-Trimethylsilylacetamide

: 111043-32-4
1-benzyl-(3-chloro-2-trimethylsilyloxypropyl)-amine

Guidance literature:: In Petroleum ether; for 3h; Heating / reflux;

Reference yield: 89.0%

: 75-77-4
chloro-trimethyl-silane

: 75605-52-6,278788-93-5
N-benzyl-3-amino-1-chloropropan-2-ol

: 111043-32-4
1-benzyl-(3-chloro-2-trimethylsilyloxypropyl)-amine

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1021/jo035759i

Reference yield:

: 100-46-9
benzylamine

: 111043-32-4
1-benzyl-(3-chloro-2-trimethylsilyloxypropyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / hexane / 15 h / 20 °C

2: 89 percent / Et₃N / CH₂Cl₂ / 3 h / 20 °C

With triethylamine; In hexane; dichloromethane;
DOI:10.1021/jo035759i