Methyl isoindoline-1-carboxylate

Base Information

Chemical Name:Methyl isoindoline-1-carboxylate
CAS No.:111605-85-7
Molecular Formula:C10H11NO2
Molecular Weight:0.00000
Hs Code.:
DSSTox Substance ID:DTXSID301254332
Mol file:111605-85-7.mol

Synonyms:Methyl isoindoline-1-carboxylate;111605-85-7;methyl 2,3-dihydro-1H-isoindole-1-carboxylate;1H-Isoindole-1-carboxylic acid, 2,3-dihydro-, methyl ester;Methylisoindoline-1-carboxylate;SCHEMBL4143242;HAHSSOBUBYFYNE-UHFFFAOYSA-N;DTXSID301254332;AKOS006373267;SB65578;EN300-3001788

Suppliers and Price of Methyl isoindoline-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl isoindoline-1-carboxylate

Chemical Property:

PSA：0.00000
LogP:0.00000
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:177.078978594
Heavy Atom Count:13
Complexity:205

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1C2=CC=CC=C2CN1

Technology Process of Methyl isoindoline-1-carboxylate

There total 26 articles about Methyl isoindoline-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 67-56-1
methanol

: 96016-96-5
1,3-Dihydro-2H-isoindole-1-carboxylic Acid Hydrochloride

: 111605-85-7
methyl (+/-)-1,3-dihydro-2H-isoindole-1-carboxylate

Guidance literature:: methanol; 1,3-Dihydro-2H-isoindole-1-carboxylic Acid Hydrochloride; With thionyl chloride; at 20 ℃; for 24h; Cooling with ice;

With sodium hydrogencarbonate; In dichloromethane; water;
DOI:10.1021/ol300250h

Reference yield:

: 444607-92-5
2-(tert-butyl) 1-methyl isoindoline-1,2-dicarboxylate

: 111605-85-7
methyl (+/-)-1,3-dihydro-2H-isoindole-1-carboxylate

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 12h;

Reference yield:

: 1367468-08-3
2-allyl 1-methyl (R)-1,3-dihydro-2H-isoindole-1,2-dicarboxylate

: 781597-60-2,111605-85-7
methyl (S)-1,3-dihydro-2H-isoindole-1-carboxylate

: 1367468-12-9,111605-85-7
methyl (R)-1,3-dihydro-2H-isoindole-1-carboxylate

Guidance literature:: With 1,3-dimethylbarbituric acid; palladium diacetate; triphenylphosphine; In dichloromethane; at 35 ℃; for 1h; Inert atmosphere;
DOI:10.1021/ol300250h