PHENYL PHENYLACETATE

Base Information

• Chemical Name: PHENYL PHENYLACETATE
• CAS No.: 722-01-0
• Molecular Formula: C14H12 O2
• Molecular Weight: 212.248
• Hs Code.: 2916340010
• Mol file: 722-01-0.mol

Synonyms:Aceticacid, phenyl-, phenyl ester (6CI,7CI,8CI); Phenyl 2-phenylacetate; Phenylbenzeneacetate; Phenyl phenylacetate

Chemical Property of PHENYL PHENYLACETATE

Chemical Property:

• Vapor Pressure: 6.11E-05mmHg at 25°C
• Melting Point: 40-42 °C(lit.)
• Refractive Index: 1.5570 (estimate)
• Boiling Point: 158 °C7 mm Hg(lit.)
• Flash Point: >230 °F
• PSA: 26.30000
• Density: 1.13g/cm³
• LogP: 2.83470

Purity/Quality:

98%,99%, ^*data from raw suppliers

Phenyl phenylacetate 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of PHENYL PHENYLACETATE

There total 38 articles about PHENYL PHENYLACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

phenylacetic acid (103-82-2) + phenol (108-95-2,27073-41-2) → phenyl phenylacetate (722-01-0)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃;

DOI:10.1016/S0957-4166(01)00114-8

Reference yield: 99.0%

carbon monoxide (201230-82-2) + benzyl bromide (100-39-0) + phenol (108-95-2,27073-41-2) → phenyl phenylacetate (722-01-0)

Guidance literature:

With rhodium(III) chloride; 1,3-bis-(diphenylphosphino)propane; sodium carbonate; sodium iodide; In 1,4-dioxane; at 120 ℃; for 24h; under 750.075 Torr; chemoselective reaction; Inert atmosphere;

DOI:10.1021/acscatal.0c00933

Reference yield: 98.0%

phenylacetic acid (103-82-2) + phenylboronic acid (98-80-6) → phenyl phenylacetate (722-01-0)

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); urea; In ethyl acetate; at 60 ℃; for 12h;

DOI:10.1021/jo101558s

upstream raw materials:

α-phenoxy-cinnamic acid

phenylacetyl chloride

phenol

phenylacetic acid

Downstream raw materials:

phenyl isocyanate

phenol

4-hydroxy-3-phenylcoumarin

2-Phenylacetoxy-benzoic acid phenyl ester

Refernces

• 1、 Huang, Changyu,Li, Jinpeng,Wang, Jiaquan,Zheng, Qingshu,Li, Zhenhua,Tu, Tao. "Hydrogen-bond-assisted transition-metal-free catalytic transformation of amides to esters". . p. 66 - 71. Retrieved 2020/11/18.
• 2、 Chang, Meng-Yang,Chen, Kuan-Ting,Chen, Shin-Mei,Hsiao, Yu-Ting. "Ac2O-Mediated Dearylacetylative Dimerization of 2-Arylacetyl-1-naphthols: Synthesis of Naphtho[1,2-b]furan-3-ones". . p. 3605 - 3616. Retrieved 2020/03/23.