(2,4,6-Tritert-butylphenyl)benzylidenephosphine

Base Information

• Chemical Name: (2,4,6-Tritert-butylphenyl)benzylidenephosphine
• CAS No.: 143372-18-3
• Molecular Formula: C₂₅H₃₅P
• Molecular Weight: 366.527
• DSSTox Substance ID: DTXSID00540592
• Nikkaji Number: J2.008.908C,J685.328E
• Wikidata: Q82416639
• Mol file: 143372-18-3.mol

Synonyms:143372-18-3;(2,4,6-Tritert-butylphenyl)benzylidenephosphine;DTXSID00540592;(E)-Benzylidene(2,4,6-tri-tert-butylphenyl)phosphane

Chemical Property of (2,4,6-Tritert-butylphenyl)benzylidenephosphine

Chemical Property:

• XLogP3: 7.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 5
• Exact Mass: 366.247638114
• Heavy Atom Count: 26
• Complexity: 438

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)C1=CC(=C(C(=C1)C(C)(C)C)P=CC2=CC=CC=C2)C(C)(C)C

Technology Process of (2,4,6-Tritert-butylphenyl)benzylidenephosphine

There total 22 articles about (2,4,6-Tritert-butylphenyl)benzylidenephosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

benzaldehyde (100-52-7) + [(2,4,6-tri-tert-butylphenyl)PPMe3] (212079-68-0) → (E)-benzylidene(2,4,6-tri-tert-butylphenyl)phosphane (99364-92-8,99364-93-9,143372-18-3)

Guidance literature:

In tetrahydrofuran;

DOI:10.1039/a802722f

Reference yield: 85.0%

phosphanylphosphonate + benzaldehyde (100-52-7) → (E)-benzylidene(2,4,6-tri-tert-butylphenyl)phosphane (99364-92-8,99364-93-9,143372-18-3)

Guidance literature:

phosphanylphosphonate; With lithium diisopropyl amide; In tetrahydrofuran; at 20 ℃; for 0.0833333h; Inert atmosphere; Schlenk technique;

benzaldehyde; In tetrahydrofuran; Inert atmosphere; Schlenk technique;

DOI:10.1039/c8cc04218g

Reference yield: 76.0%

phenylmagnesium chloride (100-59-4) + E-2-chloro-1-(2,4,6-tri-t-butylphenyl)-1-phospha-ethylene (92957-42-1,92957-44-3,100281-30-9) → (E)-benzylidene(2,4,6-tri-tert-butylphenyl)phosphane (99364-92-8,99364-93-9,143372-18-3)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; Ambient temperature;

DOI:10.1080/10426509608545221

upstream raw materials:

(2,4,6-tri-tert-butylphenyl)phosphine

benzaldehyde

t-butyldimethylsilyl(2,4,6-tri-t-butylphenyl)phosphine

lithium (t-butyldimethylsilyl)(2,4,6-tri-t-butylphenyl)phosphide

Downstream raw materials:

(E)-1,2-diphenyl-ethene

2,4,6-tri-tert-butylphenylphosphinic acid

Cu₂Cl₂(CH₃CN)2(P(C₆H₂(C(CH₃)3)3)CHC₆H₅)2

(Phenylethenyliden)(2,4,6-tri-tert-butylphenyl)phosphan