1,4,5-Trimethyl-1H-imidazole

Base Information

• Chemical Name: 1,4,5-Trimethyl-1H-imidazole
• CAS No.: 20185-22-2
• Molecular Formula: C6H10N2
• Molecular Weight: 110.15700
• Hs Code.: 2933290090
• Mol file: 20185-22-2.mol

Synonyms:1,4,5,8-Tetra-p-toluidino-anthrachinon;1,4,5-tetramethylimidazole;1,4,5-Trimethyl-1H-imidazol;1,4,5,8-tetra-p-toluidino-anthraquinone;9,10-Anthracenedione,1,4,5,8-tetrakis[(4-methylphenyl)amino];1,4,5-trimethyl-imidazole;

Chemical Property of 1,4,5-Trimethyl-1H-imidazole

Chemical Property:

• Vapor Pressure: 0.0552mmHg at 25°C
• Boiling Point: 241.6oC at 760 mmHg
• PKA: 7.92±0.61(Predicted)
• Flash Point: 99.9oC
• PSA: 17.82000
• Density: 0.97g/cm3
• LogP: 1.03690

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4,5-Trimethyl-1H-imidazole

There total 9 articles about 1,4,5-Trimethyl-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + methylamine hydrochloride (593-51-1) + dimethylglyoxal (431-03-8) → 1,4,5-Trimethylimidazole (20185-22-2)

Guidance literature:

formaldehyd; methylamine hydrochloride; With ammonium hydroxide;

dimethylglyoxal; at 100 ℃;

DOI:10.1002/ejoc.201100857

Reference yield: 68.0%

1,4,5-trimethyl-1H-imidazole 3-oxide (63455-73-2) → 1,4,5-Trimethylimidazole (20185-22-2)

Guidance literature:

With Raney nickel; In methanol; at 20 ℃;

DOI:10.1016/j.tetasy.2015.10.019

Reference yield: 57.8%

→ 1,4,5-Trimethylimidazole (20185-22-2)

Guidance literature:

upstream raw materials:

4,5-dimethylimidazole

methyl iodide

formaldehyd

methylamine hydrochloride

Downstream raw materials:

1,4,5-trimethyl-1H-imidazole-2-carbaldehyde

(1,4,5-Trimethyl-1H-imidazol-2-yl)-methanol

1,4,5-trimethylimidazole-tris(pentafluorophenyl)borane adduct

8-(4-fluorophenyl)-9-(1,4,5-trimethyl-1H-imidazol-2-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one