2,4-Difluoro-5-nitrobenzoyl chloride

Base Information

Chemical Name:2,4-Difluoro-5-nitrobenzoyl chloride
CAS No.:221560-09-4
Molecular Formula:C7H2ClF2NO3
Molecular Weight:221.548
Hs Code.:2916399090
DSSTox Substance ID:DTXSID70592720
Wikidata:Q82486977
Mol file:221560-09-4.mol

Synonyms:221560-09-4;2,4-Difluoro-5-nitrobenzoyl chloride;2,4-DIFLUORO-5-NITRO-BENZOYLCHLORIDE;Benzoyl chloride, 2,4-difluoro-5-nitro-;SCHEMBL1966853;DTXSID70592720;TYAWHJWDJPXNTO-UHFFFAOYSA-N;AKOS015995843;2,4-difluoro-5-nitro-benzoyl chloride

Suppliers and Price of 2,4-Difluoro-5-nitrobenzoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,4-Difluoro-5-nitrobenzoyl chloride

Chemical Property:

PSA：62.89000
LogP:2.77520
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:220.9691269
Heavy Atom Count:14
Complexity:258

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CC(=C1[N+](=O)[O-])F)F)C(=O)Cl

Technology Process of 2,4-Difluoro-5-nitrobenzoyl chloride

There total 4 articles about 2,4-Difluoro-5-nitrobenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.2%

: 79-37-8
oxalyl dichloride

: 153775-33-8
2,4-difluoro-5-nitro-benzoic acid

: 221560-09-4
2,4-Difluoro-5-nitrobenzoyl Chloride

Guidance literature:: In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 153775-33-8
2,4-difluoro-5-nitro-benzoic acid

: 221560-09-4
2,4-Difluoro-5-nitrobenzoyl Chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 18h;
DOI:10.1021/jm0205090

Reference yield:

: 1583-58-0
2,4-difluoro-benzoic acid

: 221560-09-4
2,4-Difluoro-5-nitrobenzoyl Chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / KNO₃; conc. H₂SO₄ / 24 h / 20 °C

2: oxalyl chloride; DMF / CH₂Cl₂ / 18 h / 20 °C

With oxalyl dichloride; sulfuric acid; potassium nitrate; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/jm0205090