3-(methylamino)-1-phenylpropan-1-one

Base Information

• Chemical Name: 3-(methylamino)-1-phenylpropan-1-one
• CAS No.: 27152-62-1
• Molecular Formula: C10H13NO
• Molecular Weight: 163.219
• Mol file: 27152-62-1.mol

Synonyms:3-(methylamino)-1-phenyl-1-propanone;3-oxo-N-methyl-3-phenylpropylamine;3-methylamino-1-phenyl-propan-1-one;1-Propanone,3-(methylamino)-1-phenyl;3-(N-methylamino)propiophenone;3-Methylamino-1-phenyl-propan-1-on;1-N-methylamino-3-phenyl-3-propanone;

Chemical Property of 3-(methylamino)-1-phenylpropan-1-one

Chemical Property:

• PSA: 29.10000
• LogP: 1.86970

Purity/Quality:

99% ^*data from raw suppliers

3-(methylamino)-1-phenylpropan-1-one 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(methylamino)-1-phenylpropan-1-one

There total 13 articles about 3-(methylamino)-1-phenylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.6%

1-(N-formyl-N-methyl)amino-3-phenylpropan-2-one (207395-42-4) → 3-(N-methylamino)propiophenone (27152-62-1)

Guidance literature:

With manganese(IV) oxide; sodium hydroxide; In ethanol; at 20 ℃; for 8h;

DOI:10.1023/A:1013841325485

Reference yield: 20.0%

1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (28289-54-5) → 3-(N-methylamino)propiophenone (27152-62-1)

Guidance literature:

With potassium permanganate; In acetonitrile; at 20 - 60 ℃; for 26h;

DOI:10.1023/A:1013841325485

Reference yield:

3-bromo-1-phenylpropan-1-one (29636-75-7) + methylamine (74-89-5) → 3-(N-methylamino)propiophenone (27152-62-1) + methylammonium bromide (6876-37-5)

Guidance literature:

In acetonitrile; at 25 ℃; Rate constant; Mechanism;

upstream raw materials:

N-methyl-3-oxo-N-(3-oxo-3-phenylpropyl)-3-phenylpropan-1-aminium chloride

formaldehyd

methylamine hydrochloride

acetophenone

Downstream raw materials:

9,10-dihydro-N-methyl-9-oxo-N-(3-oxo-3-phenylpropyl)acridine-4-carboxamide

(S)-N-methyl-3-amino-1-phenyl-1-propanol

N-<3-Phenyl-propin-(2)-yl>-N-<3-hydroxy-3-phenyl-propyl>-methylamin

N-(Methyl-β-benzoylethyl)glycine methyl ester hydrobromide