1,3-benzothiazol-2-yl(phenyl)methanone

Base Information

• Chemical Name: 1,3-benzothiazol-2-yl(phenyl)methanone
• CAS No.: 1629-75-0
• Molecular Formula: C14H9 N O S
• Molecular Weight: 239.298
• Mol file: 1629-75-0.mol

Synonyms:Ketone,2-benzothiazolyl phenyl (6CI,7CI,8CI); 2-Benzothiazolyl phenyl ketone;2-Benzoylbenzothiazole; NSC 252936

Chemical Property of 1,3-benzothiazol-2-yl(phenyl)methanone

Chemical Property:

• Vapor Pressure: 1.18E-06mmHg at 25°C
• Boiling Point: 401.5°Cat760mmHg
• Flash Point: 196.6°C
• Density: 1.297g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-benzothiazol-2-yl(phenyl)methanone

There total 112 articles about 1,3-benzothiazol-2-yl(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-amino-benzenethiol (137-07-5) + 1-Bromo-2-phenylacetylene (932-87-6) → 2-benzoylbenzothiazole (1629-75-0)

Guidance literature:

With ruthenium(III) chloride trihydrate; In water; at 80 ℃; for 6h;

DOI:10.1071/CH11217

Reference yield: 72.0%

1,3-Benzothiazole (95-16-9) + acetophenone (98-86-2) → 2-Phenylbenzothiazole (883-93-2) + 2-benzoylbenzothiazole (1629-75-0)

Guidance literature:

With copper(I) oxide; oxygen; In water; dimethyl sulfoxide; at 130 ℃; for 24h; chemoselective reaction; Sealed tube;

DOI:10.1002/adsc.201400240

Reference yield: 66.0%

1,3-Benzothiazole (95-16-9) + ethyl 3-oxo-3-phenylpropionate (94-02-0) → 2-Phenylbenzothiazole (883-93-2) + 2-benzoylbenzothiazole (1629-75-0)

Guidance literature:

With iron(III) chloride hexahydrate; oxygen; tricyclohexylphosphine tetrafluoroborate; In water; dimethyl sulfoxide; at 120 ℃; for 20h;

DOI:10.1016/j.tetlet.2013.05.050

upstream raw materials:

2-(α-hydroxybenzyl)-1,3-benzothiazole

2-(2-nitro-phenylsulfanyl)-1-phenyl-ethanone

sodium methylate

benzonitrile

Downstream raw materials:

bis(1,3-benzothiazol-2-yl)(phenyl)methanol

(1,3-benzothiazol-2-yl)(phenyl)methanone oxime

1-(2-benzothiazolyl)-2-aza-1-phenyl-1,4-pentadiene

phenyl benzyl ketone