Technology Process of 9H-Xanthene-4-carboxaldehyde,
5-bromo-2,7-bis(1,1-dimethylethyl)-9,9-dimethyl-
There total 1 articles about 9H-Xanthene-4-carboxaldehyde,
5-bromo-2,7-bis(1,1-dimethylethyl)-9,9-dimethyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: iron(III) chloride / dichloromethane / 4 h / 0 °C
2.1: bromine / acetic acid / 20 h / 50 °C
3.1: phenyllithium / tetrahydrofuran; dibutyl ether / 1.25 h / -78 °C / Inert atmosphere; Schlenk technique; Glovebox
3.2: 1 h / -78 - 20 °C / Inert atmosphere; Schlenk technique; Glovebox
With
iron(III) chloride; bromine; phenyllithium;
In
tetrahydrofuran; dichloromethane; dibutyl ether; acetic acid;
DOI:10.1039/c7dt01294b
- Guidance literature:
-
pyrrole; perfluorobenzaldehyde; 5-bromo-2,7-di-tert-butyl-9,9-dimethylxanthene-4-carbaldehyde;
In
chloroform;
for 2.5h;
Inert atmosphere;
With
boron trifluoride diethyl etherate;
In
chloroform;
for 1h;
Inert atmosphere;
Darkness;
With
2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
chloroform;
for 1h;
Inert atmosphere;
Darkness;
- Guidance literature:
-
pyrrole; mesytaldehyde; 5-bromo-2,7-di-tert-butyl-9,9-dimethylxanthene-4-carbaldehyde;
With
boron trifluoride diethyl etherate;
In
chloroform;
at 20 ℃;
for 1.41667h;
With
2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
chloroform;
for 1h;
DOI:10.1021/ol034581j
