dichloro(4-methylphenyl)borane

Base Information

• Chemical Name: dichloro(4-methylphenyl)borane
• CAS No.: 4250-45-7
• Molecular Formula: C7H7BCl2
• Molecular Weight: 172.85
• Mol file: 4250-45-7.mol

Synonyms:p-MeC6H4BCl2;<4-Methyl-phenyl>-bordichlorid;dichloro-p-tolyl-borane;p-Tolylbordichlorid;Dichlor-p-tolyl-boran;

Chemical Property of dichloro(4-methylphenyl)borane

Chemical Property:

• Vapor Pressure: 0.355mmHg at 25°C
• Melting Point: 25-27 °C
• Boiling Point: 205.6oC at 760 mmHg
• Flash Point: 78.1oC
• PSA: 0.00000
• Density: 1.14g/cm3
• LogP: 2.16780

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dichloro(4-methylphenyl)borane

There total 19 articles about dichloro(4-methylphenyl)borane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

p-(trimethylsilyl)toluene (3728-43-6) + boron trichloride (10294-34-5) → dichloro-p-tolyl-borane (4250-45-7)

Guidance literature:

In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1039/d1cc03481b

Reference yield: 70.0%

boron trichloride (10294-34-5) + tetra(p-tolyl)tin (6746-22-1) → dichloro-p-tolyl-borane (4250-45-7)

Guidance literature:

dropping BCl3 to cooled, stirred Sn(C6H4-4-CH3)4, /cooler at -74°C), boiling 3o min. under reflux;

Reference yield: 66.0%

boron trichloride (10294-34-5) + toluene (108-88-3,15644-74-3,16713-13-6) + diborane (19287-45-7) → dichloro-p-tolyl-borane (4250-45-7) + (3-CH3-C6H4)BCl2 (4250-47-9) + hydrogen (1333-74-0)

Guidance literature:

byproducts: boron hydride; High Pressure; under N2; diborane and trihalogen-borane was added to toluene at -130°C, then in a closed autoclave the mixture was heated to 120°C for 90 min; at -195.8°C H2 was removed, at room temp. the residue of trihalogen-borane and diborane were removed;

upstream raw materials:

tri(4-tolyl)boroxine

(4-CH₃-C₆H₄)B(O-i-C₄H₉)2

bis(p-tolyl)mercury

toluene

Downstream raw materials:

p-cresol

2-(4-methylphenyl)-benzo-1,3-dioxa-2-borole

2-(4-methylphenyl)-naphtho{2,3-d}-1,3-dioxa-2-borole

4-CH₃C₆H₄BClN(CH₃)(CH₂C₆H₅)

Refernces

• 1、 Yasuike, Shuji,Nakata, Kazuhide,Qin, Weiwei,Matsumura, Mio,Kakusawa, Naoki,Kurita, Jyoji. "Synthesis of arylboronates by boron-induced ipso-deantimonation of triarylstibanes with boron trihalides and its application in one-pot two-step transmetallation/cross-coupling reactions". . p. 9 - 16. Retrieved 2015/05/13.
• 2、 Paetzold, Peter,Hoffmann, Juergen. "A New Borylation Method for Alkylbenzene and Polystyrene". . p. 3724 - 3733. Retrieved 2007/10/02.