Methyl 2-bromo-2-(2-nitrophenyl)acetate

Base Information

Chemical Name:Methyl 2-bromo-2-(2-nitrophenyl)acetate
CAS No.:42794-41-2
Molecular Formula:C9H8BrNO4
Molecular Weight:274.06800
Hs Code.:2916399090
DSSTox Substance ID:DTXSID90443189
Nikkaji Number:J3.629.167B
Mol file:42794-41-2.mol

Synonyms:42794-41-2;Methyl 2-bromo-2-(2-nitrophenyl)acetate;METHYL 2-BROMO-2-(2-NITROPHENYL) ACETATE;2-Bromo-2-(2-nitrophenyl)acetic acid methyl ester;SCHEMBL4558503;DTXSID90443189;methyl bromo(2-nitrophenyl)acetate;AKOS016024004;AB10310;FT-0693582;J3.629.167B;F2147-1155

Suppliers and Price of Methyl 2-bromo-2-(2-nitrophenyl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-BROMO-2-(2-NITROPHENYL)ACETIC ACID METHYL ESTER 95.00%
5MG
$ 499.49

Total 8 raw suppliers

Chemical Property of Methyl 2-bromo-2-(2-nitrophenyl)acetate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:356.806oC at 760 mmHg
Flash Point:169.59oC
PSA：72.12000
Density:1.631g/cm3
LogP:2.72700
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:272.96367
Heavy Atom Count:15
Complexity:253

Purity/Quality:

98%min ^*data from raw suppliers

2-BROMO-2-(2-NITROPHENYL)ACETIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(C1=CC=CC=C1[N+](=O)[O-])Br

Technology Process of Methyl 2-bromo-2-(2-nitrophenyl)acetate

There total 4 articles about Methyl 2-bromo-2-(2-nitrophenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 30095-98-8
methyl (2-nitrophenyl)acetate

: 42794-41-2
methyl α-bromo-2-nitrophenylacetate

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 72h; Heating;
DOI:10.1021/jo9917846

Reference yield:

: 67-56-1
methanol

: 3740-52-1
2-(2-nitrophenyl)acetic acid

: 42794-41-2
methyl α-bromo-2-nitrophenylacetate

Guidance literature:: methanol; 2-(2-nitrophenyl)acetic acid;

With N-Bromosuccinimide; dibenzoyl peroxide; for 72h;
DOI:10.1016/j.tet.2017.02.045

Reference yield:

: 3740-52-1
2-(2-nitrophenyl)acetic acid

: 42794-41-2
methyl α-bromo-2-nitrophenylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / NaHCO₃ / dimethylformamide / 8 h

2: 22 percent / NBS; benzoyl peroxide / CCl₄ / 72 h / Heating

With N-Bromosuccinimide; sodium hydrogencarbonate; dibenzoyl peroxide; In tetrachloromethane; N,N-dimethyl-formamide; 1: Methylation / 2: Bromination;
DOI:10.1021/jo9917846