1-(Dimethoxymethyl)-4-(methoxymethyl)benzene

Base Information

• Chemical Name: 1-(Dimethoxymethyl)-4-(methoxymethyl)benzene
• CAS No.: 46316-11-4
• Molecular Formula: C11H16O3
• Molecular Weight: 196.246
• DSSTox Substance ID: DTXSID50597470
• Wikidata: Q82493019
• Mol file: 46316-11-4.mol

Synonyms:1-(Dimethoxymethyl)-4-(methoxymethyl)benzene;46316-11-4;SCHEMBL8954887;DTXSID50597470;1-dimethoxymethyl-4-methoxymethyl benzene

Chemical Property of 1-(Dimethoxymethyl)-4-(methoxymethyl)benzene

Chemical Property:

• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 196.109944368
• Heavy Atom Count: 14
• Complexity: 138

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC1=CC=C(C=C1)C(OC)OC

Technology Process of 1-(Dimethoxymethyl)-4-(methoxymethyl)benzene

There total 5 articles about 1-(Dimethoxymethyl)-4-(methoxymethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

methanol (67-56-1) + para-xylene (106-42-3) → 4-methylbenzaldehyde dimethylacetal (3395-83-3) + α,α,α'-trimethoxy-p-xylene (46316-11-4) + 3,6-dimethoxy-3,6-dimethylcyclohexa-1,4-diene (132907-18-7)

Guidance literature:

With potassium fluoride; Product distribution; Electrochemical reaction;

DOI:10.1016/S0040-4020(02)00495-7

Reference yield: 33.0%

methanol (67-56-1) + para-xylene (106-42-3) → 4-methylbenzyl methyl ether (3395-88-8) + 4-methylbenzaldehyde dimethylacetal (3395-83-3) + α,α,α'-trimethoxy-p-xylene (46316-11-4) + trans-3,6-Dimethoxy-3,6-dimethyl-1,4-cyclohexadiene (90554-26-0)

Guidance literature:

With sodium; at 35 ℃; Further byproducts given; electrolysis;

DOI:10.1021/jo00279a026

Reference yield:

para-xylene (106-42-3) → α,α,α'-trimethoxy-p-xylene (46316-11-4)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorine / 140 °C

2: methanol

With methanol; chlorine;

upstream raw materials:

p-bromomethylbenzal bromide

sodium methylate

1-chloromethyl-4-dichloromethyl-benzene

methanol

Downstream raw materials:

4-(methoxymethyl)benzaldehyde