2-(4-Methoxyphenyl)-2-piperidinoacetonitrile

Base Information

Chemical Name:2-(4-Methoxyphenyl)-2-piperidinoacetonitrile
CAS No.:15190-14-4
Molecular Formula:C14H18 N2 O
Molecular Weight:230.31
Hs Code.:2933399090
European Community (EC) Number:239-246-0
NSC Number:14858
DSSTox Substance ID:DTXSID301257774
Nikkaji Number:J218.369B
Mol file:15190-14-4.mol

Synonyms:15190-14-4;2-(4-Methoxyphenyl)-2-piperidinoacetonitrile;2-(4-methoxyphenyl)-2-piperidin-1-ylacetonitrile;2-(4-methoxyphenyl)-2-(piperidin-1-yl)acetonitrile;(4-methoxyphenyl)(piperidin-1-yl)acetonitrile;EINECS 239-246-0;N-FORMYL-N4-CINNAMYLPIPERAZINE;AI3-02752;2-(4-methoxyphenyl)-2-(1-piperidyl)acetonitrile;NSC14858;DTXSID301257774;MFCD00023707;NSC 14858;NSC-14858;AKOS002275113;AKOS016310224;CS-10074;1-(alpha-Cyano-4-methoxybenzyl)piperidine;(4-methoxyphenyl)(1-piperidinyl)acetonitrile;BB 0218622;CS-0358742;(4-methoxy-phenyl)-piperidin-1-yl-acetonitrile;alpha-(4-Methoxyphenyl)-1-piperidineacetonitrile;1-Piperidineacetonitrile, alpha-(4-methoxyphenyl)-

Suppliers and Price of 2-(4-Methoxyphenyl)-2-piperidinoacetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
ALPHA-(4-METHOXYPHENYL)-1-PIPERIDINEACETONITRILE Aldrich
250mg
$ 33.40

Matrix Scientific
2-(4-Methoxyphenyl)-2-(1-piperidyl)acetonitrile >95%
5g
$ 654.00

Matrix Scientific
2-(4-Methoxyphenyl)-2-(1-piperidyl)acetonitrile >95%
1g
$ 164.00

Matrix Scientific
2-(4-Methoxyphenyl)-2-(1-piperidyl)acetonitrile >95%
500mg
$ 122.00

American Custom Chemicals Corporation
2-(4-METHOXYPHENYL)-2-(PIPERIDIN-1-YL)ACETONITRILE 95.00%
10G
$ 1899.09

American Custom Chemicals Corporation
2-(4-METHOXYPHENYL)-2-(PIPERIDIN-1-YL)ACETONITRILE 95.00%
5G
$ 1241.40

American Custom Chemicals Corporation
2-(4-METHOXYPHENYL)-2-(PIPERIDIN-1-YL)ACETONITRILE 95.00%
1G
$ 717.19

Total 8 raw suppliers

Chemical Property of 2-(4-Methoxyphenyl)-2-piperidinoacetonitrile

Chemical Property:

Vapor Pressure:7.62E-05mmHg at 25°C
Boiling Point:342.3°Cat760mmHg
Flash Point:160.8°C
PSA：36.26000
Density:1.094g/cm³
LogP:2.68368
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:230.141913202
Heavy Atom Count:17
Complexity:269

Purity/Quality:

98%min ^*data from raw suppliers

ALPHA-(4-METHOXYPHENYL)-1-PIPERIDINEACETONITRILE Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(C#N)N2CCCCC2

Technology Process of 2-(4-Methoxyphenyl)-2-piperidinoacetonitrile

There total 11 articles about 2-(4-Methoxyphenyl)-2-piperidinoacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 110-89-4
piperidine

: 7677-24-9
trimethylsilyl cyanide

: 123-11-5
4-methoxy-benzaldehyde

: 15190-14-4
2-(4-methoxyphenyl)-2-(piperidin-1-yl)acetonitrile

Guidance literature:: With magnesium bromide; at 20 ℃; for 0.0833333h;
DOI:10.1139/V06-024

Reference yield: 73.0%

: 2591-86-8
N-Formylpiperidine

: 7677-24-9
trimethylsilyl cyanide

: 13139-86-1
4-methoxyphenyl magnesium bromide

: 15190-14-4
2-(4-methoxyphenyl)-2-(piperidin-1-yl)acetonitrile

Guidance literature:: N-Formylpiperidine; trimethylsilyl cyanide; With titanium(IV) isopropylate; In tetrahydrofuran; for 0.166667h;

4-methoxyphenyl magnesium bromide; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/ejoc.202100418