2,4,6-Heptatrienoic acid, 7-phenyl-, methyl ester, (2E,4E,6E)-

Base Information

• Chemical Name: 2,4,6-Heptatrienoic acid, 7-phenyl-, methyl ester, (2E,4E,6E)-
• CAS No.: 56495-90-0
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Mol file: 56495-90-0.mol

Synonyms:

Chemical Property of 2,4,6-Heptatrienoic acid, 7-phenyl-, methyl ester, (2E,4E,6E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4,6-Heptatrienoic acid, 7-phenyl-, methyl ester, (2E,4E,6E)-

There total 16 articles about 2,4,6-Heptatrienoic acid, 7-phenyl-, methyl ester, (2E,4E,6E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

methanol (67-56-1) + (2E,4E)-7,7-Bis-methylsulfanyl-1-phenyl-hepta-2,4,6-trien-1-ol (129611-92-3) → methyl (2E,4E,6E)-7-phenylhepta-2,4,6-trienoate (56495-90-0)

Guidance literature:

With boron trifluoride diethyl etherate; for 16h; Heating;

Reference yield: 52.0%

(E)-3-methoxycarbonyl-2-propenylidenetriphenylphosphorane (65866-00-4) + 3-phenyl-propenal (104-55-2) → methyl (2E,4E,6E)-7-phenylhepta-2,4,6-trienoate (56495-90-0)

Guidance literature:

for 1.5h;

DOI:10.1016/j.tet.2007.03.098

Reference yield: 43.0%

benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) + diethoxyphosphoryl-acetic acid ethyl ester (867-13-0) → methyl (2E,4E,6E)-7-phenylhepta-2,4,6-trienoate (56495-90-0)

Guidance literature:

benzoic acid methyl ester; With {μ-ClIr(cyclooctene)2}2; H₂SiEt₂; In dichloromethane; at 20 ℃; for 8h; Inert atmosphere;

diethoxyphosphoryl-acetic acid ethyl ester; With potassium trimethylsilonate; In tetrahydrofuran; at 20 ℃; for 0.5h;

diethoxyphosphoryl-acetic acid ethyl ester; Further stages;

DOI:10.1021/acs.orglett.5b02901

upstream raw materials:

methanol

7-phenyl-hepta-2,4,6-trienoic acid

(2E,4E)-7,7-Bis-methylsulfanyl-1-phenyl-hepta-2,4,6-trien-1-ol

(4E,6E)-1,1-Bis-methylsulfanyl-7-phenyl-hepta-1,4,6-trien-3-ol

Downstream raw materials:

5-(3-Phenyl-2-oxiranyl)-2(E),4(E)-pentadiensaeure-methylester