1,1,2-triphenylethane-1,2-diol

Base Information

• Chemical Name: 1,1,2-triphenylethane-1,2-diol
• CAS No.: 6296-95-3
• Molecular Formula: C20H18O2
• Molecular Weight: 290.362
• NSC Number: 17490
• DSSTox Substance ID: DTXSID401306035
• Nikkaji Number: J709.471J
• Mol file: 6296-95-3.mol

Synonyms:1,1,2-triphenylethane-1,2-diol;6296-95-3;Triphenylethyleneglycol;1,1,2-triphenyl-1,2-ethanediol;1,2-Ethanediol, 1,1,2-triphenyl-;1,2-Ethanediol, triphenyl- (6CI,7CI);1,1,2-triphenyl-ethane-1,2-diol;MFCD00075492;MFCD00134424;NSC17490;TimTec1_001625;Chelidonine, sulfate (salt);Oprea1_000380;1,2-Ethanediol, triphenyl-;SCHEMBL703021;C20H19NO5.xH2O4S;1,1,2-triphenyl-1,2-ethandiol;DTXSID401306035;HMS1538J19;NSC 17490;NSC-17490;AKOS004903710;NCGC00174232-01;C20-H19-N-O5.x-H2-O4-S;LS-65544;SY024767;SY024768;FT-0642292;FT-0657270;A801952

Chemical Property of 1,1,2-triphenylethane-1,2-diol

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 452.3°Cat760mmHg
• Flash Point: 210°C
• Density: 1.196g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 290.130679813
• Heavy Atom Count: 22
• Complexity: 305

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C(C2=CC=CC=C2)(C3=CC=CC=C3)O)O

Technology Process of 1,1,2-triphenylethane-1,2-diol

There total 36 articles about 1,1,2-triphenylethane-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

tetraphenylethane-1,2-diol (464-72-2) + benzaldehyde (100-52-7) → benzophenone (119-61-9) + 1,1,2-triphenyl-1,2-ethanediol (6296-95-3)

Guidance literature:

With titanium(IV) tetrabutoxide; triethylsilyl chloride; In dichloromethane; at 20 ℃;

DOI:10.1002/adsc.201200358

Reference yield: 70.0%

carbon monoxide (201230-82-2) + benzaldehyde (100-52-7) → 1,1,2-triphenyl-1,2-ethanediol (6296-95-3)

Guidance literature:

carbon monoxide; benzaldehyde; diphenyl titanium N,N'-dimethylaminotroponiminate complex; In dichloromethane; for 4h; under 517.148 - 1034.3 Torr;

With hydrogenchloride; In toluene; for 1h;

DOI:10.1021/ja992662y

Reference yield: 70.0%

benzophenone (119-61-9) + benzaldehyde (100-52-7) → 1,1,2-triphenyl-1,2-ethanediol (6296-95-3)

Guidance literature:

benzophenone; benzaldehyde; With 1,3-bis(mesityl)imidazolium chloride; dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane; copper(l) chloride; sodium t-butanolate; In tetrahydrofuran; at 80 ℃; for 6h; Inert atmosphere; Sealed tube;

With hydrogenchloride; In tetrahydrofuran; water; Reagent/catalyst;

DOI:10.1021/jacs.8b13309

upstream raw materials:

dichloro-acetic acid

diethyl ether

2-bromophenylacetic acid

benzophenone

Downstream raw materials:

benzophenone

4-isopropyl-5,5-dimethyl-2-phenyl-1,3-dioxane

Triphenylethylene

1,2,2-triphenylethan-1-one