3-o-(Methylsulfonyl)hexopyranose

Base Information

• Chemical Name: 3-o-(Methylsulfonyl)hexopyranose
• CAS No.: 61135-45-3
• Molecular Formula: C7H14O8S
• Molecular Weight: 258.249
• NSC Number: 62387
• DSSTox Substance ID: DTXSID20289613
• Mol file: 61135-45-3.mol

Synonyms:61135-45-3;3-o-(methylsulfonyl)hexopyranose;3-O-Methanesulfonyl-D-glucopyranose;NSC62387;D-Glucose 3-Methanesulfonate;DTXSID20289613;BCP31724;NSC-62387

Chemical Property of 3-o-(Methylsulfonyl)hexopyranose

Chemical Property:

• Vapor Pressure: 5.03E-16mmHg at 25°C
• Boiling Point: 583.1°C at 760 mmHg
• Flash Point: 306.4°C
• Density: 1.7g/cm³
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 258.04093857
• Heavy Atom Count: 16
• Complexity: 322

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)OC1C(C(OC(C1O)O)CO)O

Technology Process of 3-o-(Methylsulfonyl)hexopyranose

There total 4 articles about 3-o-(Methylsulfonyl)hexopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2,5,6-di-O-isopropylidene-3-O-methylsulfonyl-α-D-glucofuranose (5450-26-0) → 3-O-methylsulfonyl-D-glucose (61135-45-3) + 3-O-methylsulfonyl-D-glucose (61135-41-9)

Guidance literature:

With Amberlite IR 120 (H⁺) ion exchange resin; water; at 60 ℃; for 8h; Title compound not separated from byproducts;

DOI:10.1016/S0008-6215(96)00328-X

Reference yield:

1,2,5,6-di-O-isopropylidene-3-O-methylsulfonyl-α-D-glucofuranose (5450-26-0) → 3-O-methylsulfonyl-D-glucose (61135-45-3)

Guidance literature:

With sulfuric acid;

Reference yield:

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (582-52-5) → 3-O-methylsulfonyl-D-glucose (61135-45-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: aqueous methanol.sulfuric acid

With pyridine; sulfuric acid;

upstream raw materials:

1,2,5,6-di-O-isopropylidene-3-O-methylsulfonyl-α-D-glucofuranose

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

Downstream raw materials:

methyl-(O³,O⁴-dibenzoyl-O²-methanesulfonyl-α-D-arabinopyranoside)

O³,O⁴-dibenzoyl-O²-methanesulfonyl-β-D-arabinopyranosyl bromide

O²-methanesulfonyl-D-arabinose

O¹,O³,O⁴-tribenzoyl-O²-methanesulfonyl-β-D-arabinopyranose

Refernces