1,2-Dichloro-1,1,2-trifluoroethane

Base Information

• Chemical Name: 1,2-Dichloro-1,1,2-trifluoroethane
• CAS No.: 354-23-4
• Molecular Formula: C2H Cl2 F3
• Molecular Weight: 152.931
• European Community (EC) Number: 206-549-4
• UN Number: 1078,3163
• UNII: K8CR1MEG1D
• DSSTox Substance ID: DTXSID1042021
• Nikkaji Number: J28.334G
• Wikipedia: 1,2-Dichloro-1,1,2-trifluoroethane
• Wikidata: Q27282088
• Mol file: 354-23-4.mol

Synonyms:1,2-dichloro-1,1,2-trifluoroethane;HCFC 123a;HCFC-123a

Chemical Property of 1,2-Dichloro-1,1,2-trifluoroethane

Chemical Property:

• Vapor Pressure: 547mmHg at 25°C
• Melting Point: -78°C
• Refractive Index: 1.3430 (estimate)
• Boiling Point: 28°C
• Flash Point: °C
• PSA: 0.00000
• Density: 1.512g/cm³
• LogP: 2.35240
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 151.9407399
• Heavy Atom Count: 7
• Complexity: 64
• Transport DOT Label: Non-Flammable Gas

Purity/Quality:

99% ^*data from raw suppliers

1,2-Dichlorotrifluoroethane 98% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 23-38

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Chlorofluorocarbons
• Canonical SMILES: C(C(F)(F)Cl)(F)Cl

Technology Process of 1,2-Dichloro-1,1,2-trifluoroethane

There total 33 articles about 1,2-Dichloro-1,1,2-trifluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.8%

1,1,2-Trichloro-1,2,2-trifluoroethane (76-13-1) → 1,2-dichloro-1,2,2-trifluoroethane (354-23-4) + Chlorotrifluoroethylene (79-38-9,9036-80-0) + 1,1,2-trifluoroethylene (359-11-5)

Guidance literature:

With hydrogen; silica gel; nickel; at 450 ℃; under 760 Torr; Title compound not separated from byproducts;

DOI:10.1246/cl.1990.879

Reference yield: 80.0%

1,1,2-Trichloro-1,2,2-trifluoroethane (76-13-1) → 1,2-dichloro-1,2,2-trifluoroethane (354-23-4)

Guidance literature:

With ammonium persulfate; ammonium formate; In N,N-dimethyl-formamide; at 30 - 40 ℃;

DOI:10.1016/S0022-1139(00)81259-2

Reference yield: 49.0%

1,2-Dichloroethylene (540-59-0,43695-79-0) → 1,2-dichloro-1,2,2-trifluoroethane (354-23-4) + 1,2-difluoro-1,2-dichloroethene (431-06-1)

Guidance literature:

With hydrogen fluoride; fluorine; In 1-trifluoromethoxy-1,2-dichlorotrifluoroethane; at -45 ℃; for 4h; Inert atmosphere;

upstream raw materials:

1,1,2-trichloro-2,2-difluoroethane

1,2,2-trichloro-1,2-difluoroethane

1,2-dibromo-1,1,2-trichloroethane

1,2-dichloro-1,2,2-trifluoro-1-iodoethane

Downstream raw materials:

Chlorotrifluoroethylene

1,1,2-trifluoroethylene

hexafluoro-1,3-butadiene

1,4-dichloro-1,1,2,3,4,4-hexafluorobutane

Refernces

• 1、 Ueda, Wataru,Tomioka, Satoshi,Morikawa, Yutaka,Sudo, Motonori,Ikawa, Tsuneo. "Selective Hydrodechlorination of CFC-113 to 1-Chloro-1,2,2-trifluoroethylene over Supported Ni Catalysts". . p. 879 - 880. Retrieved 1990.
• 2、 -. "Gas phase process for chlorotrifluoroethylene". Page/Page column 12; 19-20. . Retrieved 2020/07/15.
• 3、 -. "PROCESS FOR THE FLUORINATION OF HALOOLEFINS". Page/Page column 6-7. . Retrieved 2012/02/02.