1,2,2-Trichloro-1,1-difluoroethane

Base Information

• Chemical Name: 1,2,2-Trichloro-1,1-difluoroethane
• CAS No.: 354-21-2
• Deprecated CAS: 134237-33-5,62549-18-2,712351-74-1
• Molecular Formula: C2HCl3F2
• Molecular Weight: 169.386
• Hs Code.: 2903791090
• European Community (EC) Number: 206-548-9
• DSSTox Substance ID: DTXSID00861890
• Nikkaji Number: J28.325H
• Wikidata: Q66084465
• Mol file: 354-21-2.mol

Synonyms:1,2,2-Trichloro-1,1-difluoroethane;354-21-2;1,1-Difluoro-1,2,2-trichloroethane;Frigen 122;HCFC-122;Freon 122;Ucon fluorocarbon 122;F 122 (halocarbon);HCFC 122;Trichlorodifluoroethane;Ethane, 1,2,2-trichloro-1,1-difluoro-;FC 122;1,1,2-Trichloro-2,2-difluoroethane;Difluorotrichloroethane;R 122;EINECS 206-548-9;Ethane, trichlorodifluoro-;41834-16-6;BRN 1736764;ETHANE, 1,1-DIFLUORO-1,2,2-TRICHLORO-;2,2-Difluoro-1,1,2-trichloroethane;HCFC-122 and all isomers;SCHEMBL28941;FQAMAOOEZDRHHB-UHFFFAOYSA-;DTXSID00861890;Ethane, 1,2,2-trichlorodifluoro-;Ethane, 1,2,2-trichloro-difluoro-;MFCD00039339;AKOS006229235;LS-65507;1H-Imidazole,4,5-dihydro-5,5-dimethyl-;FT-0606117;R-122;A822786

Chemical Property of 1,2,2-Trichloro-1,1-difluoroethane

Chemical Property:

• Vapor Pressure: 56.9mmHg at 25°C
• Melting Point: -141 °C
• Refractive Index: 1.39
• Boiling Point: 74.753 °C at 760 mmHg
• Flash Point: -4.27 °C
• PSA: 0.00000
• Density: 1.583 g/cm³
• LogP: 2.62170
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 167.911189
• Heavy Atom Count: 7
• Complexity: 62

Purity/Quality:

99% ^*data from raw suppliers

1,2,2-Trichloro-1,1-difluoroethane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,F
• Hazard Codes: Xi,F
• Statements: 59
• Safety Statements: 59

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Solvents -> Chlorofluorocarbons
• Canonical SMILES: C(C(F)(F)Cl)(Cl)Cl

Technology Process of 1,2,2-Trichloro-1,1-difluoroethane

There total 31 articles about 1,2,2-Trichloro-1,1-difluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.5%

1,1,2,2-tetrachloroethylene (127-18-4) → 1,1,1-trifluoro-2,2-dichloroethane (306-83-2) + 1,1,2-trichloro-2,2-difluoroethane (354-21-2)

Guidance literature:

With hydrogen fluoride; chlorine; antimony pentafluoride; at 126 - 148 ℃; for 7.1h; under 17251.7 - 20252 Torr;

Reference yield: 25.8%

1,1,2,2-tetrachloroethylene (127-18-4) → 1,1,1-trifluoro-2,2-dichloroethane (306-83-2) + 1,1,2-trichloro-2,2-difluoroethane (354-21-2) + 1,1,1,2-tetrafluoro-2-chloroethane (2837-89-0)

Guidance literature:

With hydrogen fluoride; antimony(III) fluoride; antimony pentafluoride; at 129 - 143 ℃; for 4.1h; under 17626.8 - 19502 Torr;

Reference yield: 3.1%

1,1,2,2-tetrachloroethylene (127-18-4) → 1,1,1-trifluoro-2,2-dichloroethane (306-83-2) + 1,1,2-trichloro-2,2-difluoroethane (354-21-2) + freon-121 (354-14-3) + 1,1,1,2-tetrafluoro-2-chloroethane (2837-89-0)

Guidance literature:

With hydrogen fluoride; antimony(III) fluoride; antimony pentafluoride; at 125 - 139 ℃; for 3.7h; under 16351.6 - 18376.8 Torr;

upstream raw materials:

1,1,2,2-tetrachloroethylene

1,1-difluoroethane

1-Chloro-1,1-difluoroethane

1,1-dichloro-2,2-difluoroethane

Downstream raw materials:

N-[4-(2,2-Dichloro-1,1-difluoro-ethoxy)-3-methyl-phenyl]-acetamide

1-(2,2-Dichloro-1,1-difluoro-ethoxy)-2-nitro-benzene

2-Chloro-1-(2,2-dichloro-1,1-difluoro-ethoxy)-4-nitro-benzene

1-(2,2-Dichloro-1,1-difluoro-ethoxy)-2-methoxy-4-nitro-benzene

Refernces

• 1、 -. "Manufacturing method of HCFC-123 and/or HCFC-122". Paragraph 0139-0141. . Retrieved 2019/12/25.
• 2、 Brunet, Sylvette. "Examples of catalytic and selective routes for fluorinated building blocks". . p. 1067 - 1071. Retrieved 2014/11/27.