Methyl (2-methoxyphenyl)acetate

Base Information

• Chemical Name: Methyl (2-methoxyphenyl)acetate
• CAS No.: 27798-60-3
• Molecular Formula: C10H12 O3
• Molecular Weight: 180.203
• Hs Code.: 2918990090
• European Community (EC) Number: 248-662-1
• NSC Number: 245109
• UNII: K3NWF99XPP
• DSSTox Substance ID: DTXSID60182119
• Nikkaji Number: J109.258H
• Wikidata: Q72492660
• Mol file: 27798-60-3.mol

Synonyms:27798-60-3;Methyl 2-Methoxyphenylacetate;methyl 2-(2-methoxyphenyl)acetate;Methyl (2-methoxyphenyl)acetate;2-Methoxyphenylacetic Acid Methyl Ester;Methyl o-methoxyphenylacetate;2-Methoxyphenylacetic acid methyl;Benzeneacetic acid, 2-methoxy-, methyl ester;MFCD02093479;K3NWF99XPP;EINECS 248-662-1;NSC-245109;Acetic acid, (o-methoxyphenyl)-, methyl ester;UNII-K3NWF99XPP;methyl a-methoxyphenylacetate;Methyl 2-methoxybenzeneacetate;SCHEMBL468013;methyl(2-methoxyphenyl)acetate;Methyl 2-methoxy-benzeneacetate;SCHEMBL6554270;DTXSID60182119;CBA79860;NSC245109;AKOS000296288;AM84149;NSC 245109;s11983;(2-methoxyphenyl)acetic acid methyl ester;AS-66129;SY053750;Methyl ester of o-Methoxyphenylacetic acid;(2-Methoxy-phenyl)-acetic acid methyl ester;CS-0083149;FT-0638724;M1329;EN300-748915;2-METHOXY PHENYL ACETIC ACID METHYL ESTER;A819197;2-Hydroxyphenylacetic acid, methyl ether, methyl ester

Chemical Property of Methyl (2-methoxyphenyl)acetate

Chemical Property:

• Vapor Pressure: 0.0334mmHg at 25°C
• Melting Point: 70.3-71.0 °C(Solv: ethanol, 41% (64-17-5))
• Refractive Index: 1.5160-1.5200
• Boiling Point: 242.8°Cat760mmHg
• Flash Point: 94.8°C
• PSA: 35.53000
• Density: 1.083g/cm³
• LogP: 1.41070
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 180.078644241
• Heavy Atom Count: 13
• Complexity: 168

Purity/Quality:

97% ^*data from raw suppliers

2-MethoxyphenylaceticAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Statements: 10
• Safety Statements: 16

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1CC(=O)OC
• Uses: 2-Methoxyphenylacetic Acid Methyl Ester was used to obtain NMR spectral data for aromatics and phenylacetic acid derivatives.

Technology Process of Methyl (2-methoxyphenyl)acetate

There total 16 articles about Methyl (2-methoxyphenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ methyl 2-(2-methoxyphenyl)acetate (27798-60-3)

Guidance literature:

Reference yield: 98.0%

methanol (67-56-1) + 2-methoxyphenylacetic acid (93-25-4) → methyl 2-(2-methoxyphenyl)acetate (27798-60-3)

Guidance literature:

With thionyl chloride; at 0 ℃; for 1h;

DOI:10.1002/hlca.200390036

Reference yield: 94.0%

2-Hydroxyphenylacetic acid (614-75-5) + methyl iodide (74-88-4) → methyl 2-(2-methoxyphenyl)acetate (27798-60-3)

Guidance literature:

With potassium carbonate; In acetonitrile; for 15h; Heating / reflux;

upstream raw materials:

diazomethane

2-methoxyphenylacetic acid

methyl diazoacetate

methoxybenzene

Downstream raw materials:

1-(2-methoxy-phenyl)-2-methyl-propan-2-ol

methyl 2-(2-methoxyphenyl)prop-2-enoate

(2S,5S)-2-Benzyloxycarbonylamino-5-(2-methoxy-phenyl)-hexanedioic acid 1-tert-butyl ester 6-methyl ester

(2R,5S)-2-Benzyloxycarbonylamino-5-(2-methoxy-phenyl)-hexanedioic acid 1-tert-butyl ester 6-methyl ester