6-Chloro-2-methoxynicotinic acid

Base Information

Chemical Name:6-Chloro-2-methoxynicotinic acid
CAS No.:65515-33-5
Molecular Formula:C7H6ClNO3
Molecular Weight:187.583
Hs Code.:2933399090
DSSTox Substance ID:DTXSID40605518
Nikkaji Number:J3.025.870C
Wikidata:Q82503805

Synonyms:6-CHLORO-2-METHOXYNICOTINIC ACID;65515-33-5;6-chloro-2-methoxypyridine-3-carboxylic acid;MFCD11847277;3-Pyridinecarboxylic acid, 6-chloro-2-methoxy-;SCHEMBL6742273;2-methoxy-6-chloronicotinic acid;DTXSID40605518;BWEDPOXJDWAJGX-UHFFFAOYSA-N;AKOS012682457;6-CHLORO-2-METHOXYNICOTINICACID;AB64672;CS-W005303;FF-0743;SY105262;DB-073625;C76053;EN300-151740;A867653;J-518524

Suppliers and Price of 6-Chloro-2-methoxynicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-2-methoxynicotinicacid
100mg
$ 220.00

TRC
6-Chloro-2-methoxynicotinicacid
50mg
$ 130.00

SynQuest Laboratories
6-Chloro-2-methoxypyridine-3-carboxylic acid
1 g
$ 125.00

SynQuest Laboratories
6-Chloro-2-methoxypyridine-3-carboxylic acid
250 mg
$ 45.00

Matrix Scientific
6-Chloro-2-methoxypyridine-3-carboxylic acid 95+%
1g
$ 234.00

Matrix Scientific
6-Chloro-2-methoxypyridine-3-carboxylic acid 95+%
500mg
$ 152.00

Crysdot
6-Chloro-2-methoxynicotinicacid 95+%
10g
$ 1079.00

Crysdot
6-Chloro-2-methoxynicotinicacid 95+%
25g
$ 1880.00

Crysdot
6-Chloro-2-methoxynicotinicacid 95+%
5g
$ 700.00

Crysdot
6-Chloro-2-methoxynicotinicacid 95+%
250mg
$ 136.00

Total 17 raw suppliers

Chemical Property of 6-Chloro-2-methoxynicotinic acid

Chemical Property:

Boiling Point:322.7±37.0 °C(Predicted)
PKA:3.13±0.10(Predicted)
PSA：59.42000
Density:1.430±0.06 g/cm3(Predicted)
LogP:1.44180
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:187.0036207
Heavy Atom Count:12
Complexity:176

Purity/Quality:

97% ^*data from raw suppliers

6-Chloro-2-methoxynicotinicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=N1)Cl)C(=O)O

Technology Process of 6-Chloro-2-methoxynicotinic acid

There total 3 articles about 6-Chloro-2-methoxynicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38496-18-3
2,6-dichloropyridine-3-carboxylic acid

: 124-41-4
sodium methylate

: 65515-33-5
6-chloro-2-methoxypyridine-3-carboxylic acid

: 503000-87-1
2-chloro-6-methoxypyridine-3-carboxylic acid

Guidance literature:: With methanol; at 70 ℃; for 5h; Overall yield = 69 %; Overall yield = 20.22 g;

Reference yield:

: 67-56-1
methanol

: 38496-18-3
2,6-dichloropyridine-3-carboxylic acid

: 65515-33-5
6-chloro-2-methoxypyridine-3-carboxylic acid

: 16727-43-8
2,6-dimethoxynicotinic acid

: 503000-87-1
2-chloro-6-methoxypyridine-3-carboxylic acid

Guidance literature:: With potassium tert-butylate; at 60 ℃; for 1h; regioselective reaction; Microwave irradiation;
DOI:10.1055/s-0030-1259283