2-METHOXY-PENT-4-YNOIC ACID ETHYL ESTER

Base Information

Chemical Name:2-METHOXY-PENT-4-YNOIC ACID ETHYL ESTER
CAS No.:66313-10-8
Molecular Formula:C₈H₁₂O₃
Molecular Weight:156.181
Hs Code.:

Synonyms:2-METHOXY-PENT-4-YNOIC ACID ETHYL ESTER;

Suppliers and Price of 2-METHOXY-PENT-4-YNOIC ACID ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-METHOXY-PENT-4-YNOIC ACID ETHYL ESTER 95.00%
5MG
$ 495.98

Total 2 raw suppliers

Chemical Property of 2-METHOXY-PENT-4-YNOIC ACID ETHYL ESTER

Chemical Property:

Vapor Pressure:0.242mmHg at 25°C
Boiling Point:206oC at 760 mmHg
Flash Point:77.5oC
PSA：35.53000
Density:1.01g/cm3
LogP:0.58780

Purity/Quality:

99% ^*data from raw suppliers

2-METHOXY-PENT-4-YNOIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-METHOXY-PENT-4-YNOIC ACID ETHYL ESTER

There total 2 articles about 2-METHOXY-PENT-4-YNOIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 89898-34-0
2-hydroxy-4-pentynoic acid ethyl ester

: 74-88-4
methyl iodide

: 66313-10-8
2-Methoxy-pent-4-ynoic acid ethyl ester

Guidance literature:: With sodium hydride; In tetrahydrofuran;
DOI:10.1021/jo050400a

Reference yield:

: 623-73-4
diazoacetic acid ethyl ester

: 627-41-8
propargyl alcohol methyl ether

: 66313-10-8
2-Methoxy-pent-4-ynoic acid ethyl ester

Guidance literature:: at 5 - 10 ℃; for 50h; Irradiation;
DOI:10.1016/0040-4020(77)88027-7

Reference yield:

: 66313-10-8
2-Methoxy-pent-4-ynoic acid ethyl ester

: 862658-52-4
1-[2-(5-hydroxy-4-methoxy-hepta-1,6-diynyl)-4-methyl-phenyl]-ethanone

Guidance literature:: Multi-step reaction with 5 steps

1.1: LiAlH₄ / tetrahydrofuran

2.1: 61 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / -70 - 20 °C

3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C

3.2: 58 percent / tetrahydrofuran; hexane / -78 - 20 °C

4.1: triethylamine / PdCl₂(PPh₃)2; CuI / 5 h / 80 °C

5.1: 304 mg / n-Bu₄NF / tetrahydrofuran / 2.5 h / 20 °C

With lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; tetrabutyl ammonium fluoride; dimethyl sulfoxide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In tetrahydrofuran; hexane; dichloromethane; 2.1: Swern oxidation / 4.1: Sonogashira reaction;
DOI:10.1021/jo050400a