4-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-1,3-dioxolan-2-one (non-preferred name)

Base Information

• Chemical Name: 4-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-1,3-dioxolan-2-one (non-preferred name)
• CAS No.: 2875-90-3
• Molecular Formula: C10H14 O7
• Molecular Weight: 246.217
• Mol file: 2875-90-3.mol

Synonyms:Glucofuranose,1,2-O-isopropylidene-, cyclic 5,6-carbonate, a-D- (6CI,7CI,8CI); Carbonic acid, cyclic 5,6-esterwith 1,2-O-isopropylidene-a-D-glucofuranose; Furo[2,3-d]-1,3-dioxole, a-D-glucofuranose deriv.; NSC 36890

Chemical Property of 4-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-1,3-dioxolan-2-one (non-preferred name)

Chemical Property:

• Vapor Pressure: 1.08E-10mmHg at 25°C
• Boiling Point: 467.2°Cat760mmHg
• Flash Point: 188.5°C
• Density: 1.427g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-1,3-dioxolan-2-one (non-preferred name)

There total 1 articles about 4-(6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-1,3-dioxolan-2-one (non-preferred name) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-glucose (50-99-7) + acetone (67-64-1) → 5,6-O-carbonyl-1,2-O-isopropylidene-α-D-glucofuranose (2875-90-3) + 1,2-O-isopropylidene-α-D-glucofuranose (18549-40-1) + 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (582-52-5)

Guidance literature:

beim Einleiten von Phosgen in eine Suspension;

DOI:10.1039/jr9290002796

Reference yield:

5,6-O-carbonyl-1,2-O-isopropylidene-α-D-glucofuranose (2875-90-3) → ethyl β-D-glucofuranoside (25320-77-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen chloride

2: aq. NaOH solution

With hydrogenchloride; sodium hydroxide;

DOI:10.1039/jr9290002796

Reference yield:

ethanol (64-17-5) + 5,6-O-carbonyl-1,2-O-isopropylidene-α-D-glucofuranose (2875-90-3) → ethyl-(O5,O6-carbonyl-α-D-glucofuranoside) (907572-29-6) + ethyl-(O5,O6-carbonyl-β-D-glucofuranoside) (46687-78-9)

Guidance literature:

With hydrogenchloride;

DOI:10.1039/jr9290002796

upstream raw materials:

D-glucose

acetone

Downstream raw materials:

ethyl-(O⁵,O⁶-carbonyl-α-D-glucofuranoside)

ethyl-(O⁵,O⁶-carbonyl-β-D-glucofuranoside)

O³-benzoyl-O⁵,O⁶-carbonyl-O¹,O²-isopropylidene-α-D-glucofuranose

5,6-O-carbonyl-1,2-O-isopropylidene-3-O-tosyl-α-D-glucofuranose