methyl 1-benzyl-1H-indole-2-carboxylate

Base Information

Chemical Name:methyl 1-benzyl-1H-indole-2-carboxylate
CAS No.:81787-92-0
Molecular Formula:C17H15NO2
Molecular Weight:265.312
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20358479
Nikkaji Number:J852.697D
Wikidata:Q82139082
Mol file:81787-92-0.mol

Synonyms:methyl 1-benzyl-1H-indole-2-carboxylate;81787-92-0;methyl 1-benzylindole-2-carboxylate;SCHEMBL7884326;DTXSID20358479;CCG-356386;BS-25930;CS-0205317;AG-777/36178011

Suppliers and Price of methyl 1-benzyl-1H-indole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl1-benzyl-1H-indole-2-carboxylate 95+%
5g
$ 662.00

Chemenu
methyl1-benzyl-1H-indole-2-carboxylate 95%
5g
$ 626.00

American Custom Chemicals Corporation
1-(PHENYLMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 497.56

Alichem
Methyl1-benzyl-1H-indole-2-carboxylate
1g
$ 400.00

Total 5 raw suppliers

Chemical Property of methyl 1-benzyl-1H-indole-2-carboxylate

Chemical Property:

PSA：31.23000
LogP:3.47620
Storage Temp.:2-8°C
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:265.110278721
Heavy Atom Count:20
Complexity:338

Purity/Quality:

95+% ^*data from raw suppliers

Methyl1-benzyl-1H-indole-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC2=CC=CC=C2N1CC3=CC=CC=C3

Technology Process of methyl 1-benzyl-1H-indole-2-carboxylate

There total 7 articles about methyl 1-benzyl-1H-indole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.3%

: 1202-04-6
indole-2-carboxylic acid methyl ester

: 100-39-0
benzyl bromide

: 81787-92-0
1-benzyl-1H-indole-2-carboxylic acid methyl ester

Guidance literature:: indole-2-carboxylic acid methyl ester; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

benzyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 5h;
DOI:10.1248/cpb.47.1538

Reference yield: 70.0%

: 863870-48-8
benzyl-[2-(2,2-dibromovinyl)-phenyl]-amine

: 67-56-1
methanol

: 201230-82-2
carbon monoxide

: 81787-92-0
1-benzyl-1H-indole-2-carboxylic acid methyl ester

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In tetrahydrofuran; at 110 ℃; for 20h; under 7600.51 Torr; Autoclave;
DOI:10.1021/ol801985q

Reference yield: 67.0%

: 1314970-64-3
methyl 1-(2-bromobenzyl)indoline-2-carboxylate

: 173532-06-4
methyl 1-benzylindoline-2-carboxylate

: 81787-92-0
1-benzyl-1H-indole-2-carboxylic acid methyl ester

Guidance literature:: With tri-n-butyl-tin hydride; 1,1'-azobis(1-cyanocyclohexanenitrile); In toluene; for 18h; Reflux; Inert atmosphere;
DOI:10.1039/c1ob05527e