Pyrrolidine-3-carboxylic acid

Base Information

Chemical Name:Pyrrolidine-3-carboxylic acid
CAS No.:59378-87-9
Molecular Formula:C5H9NO2
Molecular Weight:115.13
Hs Code.:2933990090
European Community (EC) Number:696-313-0
UNII:XQ9918NB1D
DSSTox Substance ID:DTXSID20900992
Nikkaji Number:J457.359E
Wikidata:Q27293960
ChEMBL ID:CHEMBL4586784
Mol file:59378-87-9.mol

Synonyms:P-3-carboxylic acid;pyrrolidine-3-carboxylic acid;S-pyrrolidine-3-carboxylic acid

Suppliers and Price of Pyrrolidine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Pyrrolidine-3-carboxylicacid
5g
$ 140.00

TRC
Pyrrolidine-3-carboxylicacid
10g
$ 200.00

TRC
Pyrrolidine-3-carboxylicacid
1g
$ 45.00

SynQuest Laboratories
3-Pyrrolidine carboxylic acid 95%
25 g
$ 310.00

SynQuest Laboratories
3-Pyrrolidine carboxylic acid 95%
1 g
$ 60.00

SynQuest Laboratories
3-Pyrrolidine carboxylic acid 95%
5 g
$ 90.00

Matrix Scientific
Pyrrolidine-3-carboxylic acid trifluoroacetate 97%
5g
$ 198.00

Matrix Scientific
Pyrrolidine-3-carboxylic acid >95%
5g
$ 132.00

Matrix Scientific
Pyrrolidine-3-carboxylic acid trifluoroacetate 97%
1g
$ 85.00

Matrix Scientific
Pyrrolidine-3-carboxylic acid trifluoroacetate 97%
25g
$ 685.00

Total 76 raw suppliers

Chemical Property of Pyrrolidine-3-carboxylic acid

Chemical Property:

Vapor Pressure:0.00615mmHg at 25°C
Melting Point:183-185 °C(Solv: methanol (67-56-1); acetone (67-64-1))
Refractive Index:1.487
Boiling Point:252.2 °C at 760 mmHg
PKA:3.86±0.20(Predicted)
Flash Point:106.3 °C
PSA：86.63000
Density:1.186 g/cm³
LogP:0.64260
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Solubility.:Methanol (Sparingly, Sonicated), Water (Slightly)
XLogP3:-3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:115.063328530
Heavy Atom Count:8
Complexity:103

Purity/Quality:

99%, ^*data from raw suppliers

Pyrrolidine-3-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39-36

MSDS Files:

Useful:

Canonical SMILES:C1CNCC1C(=O)O

Technology Process of Pyrrolidine-3-carboxylic acid

There total 10 articles about Pyrrolidine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 1.8%

: 123-75-1
pyrrolidine

: 64-18-6
formic acid

: 59378-87-9,68464-02-8,72580-53-1,72580-54-2
pyrrolidine-3-carboxylic acid

: 56-40-6,18875-39-3,25718-94-9
glycine

: 609-36-9,25191-13-3,37159-97-0,4305-67-3,4607-28-7
rac-Pro-OH

Guidance literature:: In water; at 10 - 20 ℃; for 1h; contact glow discharge electrolysis (500-600 V, 45 mA);

Reference yield: 0.4%

: 123-75-1
pyrrolidine

: 141-53-7
sodium formate

: 59378-87-9,68464-02-8,72580-53-1,72580-54-2
pyrrolidine-3-carboxylic acid

: 56-40-6,18875-39-3,25718-94-9
glycine

: 609-36-9,25191-13-3,37159-97-0,4305-67-3,4607-28-7
rac-Pro-OH

Guidance literature:: In water; at 10 - 20 ℃; for 1h; contact glow discharge electrolysis (500-600 V, 45 mA);

Reference yield:

: 191348-04-6
C₁₀H₁₇NO₃

: 59378-87-9,68464-02-8,72580-53-1,72580-54-2
pyrrolidine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: pyridinium dichromate / N,N-dimethyl-formamide; toluene / 20 °C

2: hydrogenchloride / water

With hydrogenchloride; pyridinium dichromate; In water; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ja210117z