Methyl 2,4-dichloro-6-methoxybenzoate

Base Information

Chemical Name:Methyl 2,4-dichloro-6-methoxybenzoate
CAS No.:94294-10-7
Molecular Formula:C9H8Cl2O3
Molecular Weight:235.067
Hs Code.:
DSSTox Substance ID:DTXSID801286017

Synonyms:94294-10-7;Benzoic acid, 2,4-dichloro-6-methoxy-, methyl ester;methyl 2,4-dichloro-6-methoxybenzoate;SCHEMBL17063602;DTXSID801286017

Suppliers and Price of Methyl 2,4-dichloro-6-methoxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 2,4-dichloro-6-methoxybenzoate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:233.9850495
Heavy Atom Count:14
Complexity:210

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C(=CC(=C1)Cl)Cl)C(=O)OC

Technology Process of Methyl 2,4-dichloro-6-methoxybenzoate

There total 4 articles about Methyl 2,4-dichloro-6-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 67-56-1
methanol

: 94278-69-0
2,6-dichloro-4-methoxybenzoic acid

: 94294-09-4
2,4-dichloro-6-methoxybenzoic acid

: 94294-10-7
methyl 2,4-dichloro-6-methoxybenzoate

: 94278-65-6
methyl 2,6-dichloro-4-methoxybenzoate

Guidance literature:: 2,6-dichloro-4-methoxybenzoic acid; 2,4-dichloro-6-methoxybenzoic acid; With thionyl chloride; at 20 ℃; Reflux;

methanol; With pyridine; at 20 ℃;

Reference yield:

: 99725-34-5
2,4-dichloro-6-hydroxybenzoic acid

: 74-88-4
methyl iodide

: 94294-10-7
methyl 2,4-dichloro-6-methoxybenzoate

Guidance literature:: With potassium carbonate; Yield given. Multistep reaction; 1.) DMF, 50 deg C, 0.5 h, 2.) DMF, 50 deg C, 1 h;
DOI:10.1021/jm00152a002

Reference yield:

: 33719-74-3
3,5-dichloroanisole

: 94294-10-7
methyl 2,4-dichloro-6-methoxybenzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / tetrahydrofuran / 2 h / -78 °C

1.2: 2 h

2.1: thionyl chloride / 20 °C / Reflux

2.2: 20 °C

With n-butyllithium; thionyl chloride; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran;