METHYL 2-CHLORO-3,5-DINITROBENZOATE

Base Information

• Chemical Name: METHYL 2-CHLORO-3,5-DINITROBENZOATE
• CAS No.: 2213-79-8
• Molecular Formula: C8H5ClN2O6
• Molecular Weight: 260.59
• Hs Code.: 2916399090
• Mol file: 2213-79-8.mol

Synonyms:NSC 66543;

Chemical Property of METHYL 2-CHLORO-3,5-DINITROBENZOATE

Chemical Property:

• Vapor Pressure: 3.95E-06mmHg at 25°C
• Melting Point: 90 °C
• Refractive Index: 1.603
• Boiling Point: 384.9 °C at 760 mmHg
• Flash Point: 186.6 °C
• PSA: 117.94000
• Density: 1.599 g/cm³
• LogP: 2.98940

Purity/Quality:

90%,98% ^*data from raw suppliers

METHYL 2-CHLORO-3,5-DINITROBENZOATE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 2-CHLORO-3,5-DINITROBENZOATE

There total 4 articles about METHYL 2-CHLORO-3,5-DINITROBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

methanol (67-56-1) + 2-chloro-3,5-dinitrobenzoic acid (2497-91-8) → methyl 2-chloro-3,5-dinitrobenzoate (2213-79-8)

Guidance literature:

With sulfuric acid; for 12h; Reflux;

DOI:10.1016/j.bmcl.2020.127697

Reference yield:

methyl-3,5-dinitrosalicylate (22633-33-6) + p-toluenesulfonyl chloride (98-59-9) → methyl 2-chloro-3,5-dinitrobenzoate (2213-79-8)

Guidance literature:

With N,N-diethylaniline;

Reference yield:

methanol (67-56-1) + 2-chloro-3,5-dinitrobenzoyl chloride (42747-54-6) → methyl 2-chloro-3,5-dinitrobenzoate (2213-79-8)

Guidance literature:

upstream raw materials:

methanol

2-chloro-3,5-dinitrobenzoyl chloride

2-chloro-3,5-dinitrobenzoic acid

methyl-3,5-dinitrosalicylate

Downstream raw materials:

Methyl-2-(4-methyl-1-piperazinyl)-3,5-dinitrobenzoate

2-(3,5-Diamino-2-chlorophenyl)benzimidazole

3,5-Diamino-N-(2-aminophenyl)-2-chlorobenzamide

2-(2-Chloro-3,5-diisothiocyanatophenyl)benzimidazole

Refernces

• 1、 Dudova, Katerina,Castek, Frantisek,Machacek, Vladimir,Simunek, Petr. "Preparation of substituted methyl o-nitrophenyl sulfides". . p. 7 - 17. Retrieved 2007/10/03.