Chemical Property of 4-O-beta-D-Galactopyranosyl-alpha-D-fructose
Chemical Property:
- Appearance/Colour:White powder
- Vapor Pressure:2.43E-28mmHg at 25°C
- Melting Point:~169 °C (dec.)
- Refractive Index:1,45-1,47
- Boiling Point:680.5 °C at 760 mmHg
- PKA:11.67±0.20(Predicted)
- Flash Point:365.4 °C
- PSA：197.37000
- Density:1.77 g/cm3
- LogP:-5.55300
- Storage Temp.:Refrigerator
- Solubility.:Freely soluble in water, sparingly soluble in methanol, practically insoluble in toluene.
- Water Solubility.:76.4 G/100 ML (30 ºC)
- XLogP3:-4.3
- Hydrogen Bond Donor Count:8
- Hydrogen Bond Acceptor Count:11
- Rotatable Bond Count:5
- Exact Mass:342.11621151
- Heavy Atom Count:23
- Complexity:395
- Purity/Quality:
-
99% *data from raw suppliers
Lactulose *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Safety Statements:
24/25
- MSDS Files:
-
Total 1 MSDS from other Authors
Useful:
- Canonical SMILES:C(C1C(C(C(C(O1)OC2C(OC(C2O)(CO)O)CO)O)O)O)O
- Isomeric SMILES:C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@]([C@H]2O)(CO)O)CO)O)O)O)O
- Recent ClinicalTrials:Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF)
- Recent EU Clinical Trials:RANDOMIZED, MULTICENTRIC CLINICAL TRIAL, COMPARISON BETWEEN LACTITOL AND LACTULOSE AS SUBSTRATES BREATH TEST FOR THE DIAGNOSIS OF BACTERIAL OVERGROWTH
- Recent NIPH Clinical Trials:Breath test with small intestinal bacterial overgrowth
-
Uses
Lactulose is is a synthetic, non-digestible sugar used in the treatment of chronic constipation; laxative. pharmaceutical excipient A keto analogue of lactose.
-
Indications
Osmotic laxatives (e.g., lactulose, sorbitol) are poorly
absorbed or nonabsorbable compounds that draw additional
fluid into the GI tract. Lumen osmolality increases,
and fluid movement occurs secondary to osmotic
pressure. Lactulose is a synthetic disaccharide
that is poorly absorbed from the GI tract, since no
mammalian enzyme is capable of hydrolyzing it to its
monosaccharide components. It therefore reaches the
colon unchanged and is metabolized by colonic bacteria
to lactic acid and to small quantities of formic and acetic
acids.
-
Clinical Use
Lactulose is used in the
treatment of hepatic encephalopathy.
