tert-Butyl thiazol-4-ylcarbamate

Base Information

Chemical Name:tert-Butyl thiazol-4-ylcarbamate
CAS No.:1235406-42-4
Molecular Formula:C8H12N2O2S
Molecular Weight:200.261
Hs Code.:
European Community (EC) Number:862-884-1
DSSTox Substance ID:DTXSID70692875
Wikidata:Q82621913
Mol file:1235406-42-4.mol

Synonyms:tert-Butyl thiazol-4-ylcarbamate;1235406-42-4;tert-butyl N-(1,3-thiazol-4-yl)carbamate;4-(Boc-amino)thiazole;tert-Butyl thiazol-4-yl-carbamate;4-(BOC-AMINO)-THIAZOLE;MFCD18800853;tert-butyl 1,3-thiazol-4-ylcarbamate;Thiazol-4-ylcarbamic acid tert-butyl ester;SCHEMBL165039;Carbamic acid, N-4-thiazolyl-, 1,1-dimethylethyl ester;DTXSID70692875;NNPOFSOQPYVUDW-UHFFFAOYSA-N;BCP11598;CS-B0999;AKOS008154414;GS-3975;SB32083;AC-29434;SY027632;thiazol-4-yl-carbamic acid tert-butyl ester;AM20080178;FT-0751036;thiazole-4-yl-carbamic acid tert-butyl ester;EN300-84948;A23978;A1-01007

Suppliers and Price of tert-Butyl thiazol-4-ylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-ButylThiazol-4-ylcarbamate
50mg
$ 45.00

Medical Isotopes, Inc.
tert-Butylthiazol-4-ylcarbamate 95+%
1000 mg
$ 500.00

Medical Isotopes, Inc.
tert-Butylthiazol-4-ylcarbamate 95+%
250 mg
$ 380.00

Matrix Scientific
tert-Butyl thiazol-4-ylcarbamate 95+%
250mg
$ 231.00

Matrix Scientific
tert-Butyl thiazol-4-ylcarbamate 95+%
1g
$ 500.00

Matrix Scientific
tert-Butyl thiazol-4-ylcarbamate 95+%
5g
$ 1340.00

J&W Pharmlab
tert-Butylthiazol-4-yl-carbamate 97%
25g
$ 798.00

J&W Pharmlab
tert-Butylthiazol-4-yl-carbamate 97%
5g
$ 198.00

J&W Pharmlab
tert-Butylthiazol-4-yl-carbamate 97%
1g
$ 55.00

Frontier Specialty Chemicals
tert-ButylN-(1,3-thiazol-4-yl)carbamate
1g
$ 120.00

Total 45 raw suppliers

Chemical Property of tert-Butyl thiazol-4-ylcarbamate

Chemical Property:

Melting Point:153-155 °C
Boiling Point:254.9±13.0 °C(Predicted)
PKA:12.39±0.70(Predicted)
PSA：79.46000
Density:1.242±0.06 g/cm3(Predicted)
LogP:2.56310
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:200.06194880
Heavy Atom Count:13
Complexity:191

Purity/Quality:

99%, ^*data from raw suppliers

tert-ButylThiazol-4-ylcarbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CSC=N1

Technology Process of tert-Butyl thiazol-4-ylcarbamate

There total 2 articles about tert-Butyl thiazol-4-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 766-98-3
1-ethynyl-4-fluorobenzene

: 1258934-68-7
tert-butyl N-(5-iodo-1,3-thiazol-4-yl)carbamate

: 1235406-42-4
thiazol-4-ylaminocarboxylic acid tert-butyl ester

: 1258934-71-2
tert-butyl N-{5-[2-(4-fluorophenyl)ethynyl]-1,3-thiazol-4-yl}carbamate

Guidance literature:: With palladium diacetate; sodium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 20h;
DOI:10.1055/s-0030-1258159

Reference yield:

: 766-98-3
1-ethynyl-4-fluorobenzene

: 1258934-68-7
tert-butyl N-(5-iodo-1,3-thiazol-4-yl)carbamate

: 1235406-42-4
thiazol-4-ylaminocarboxylic acid tert-butyl ester

: 1258934-72-3
C₁₁H₇FN₂S

: 1258934-71-2
tert-butyl N-{5-[2-(4-fluorophenyl)ethynyl]-1,3-thiazol-4-yl}carbamate

Guidance literature:: With tetrabutylammonium acetate; palladium diacetate; In acetonitrile; for 17h; Reflux;
DOI:10.1055/s-0030-1258159

Reference yield: 85.0%

: 1235406-42-4
thiazol-4-ylaminocarboxylic acid tert-butyl ester

: 175278-08-7
2,3,4-trifluorobenzenesulfonyl chloride

: tert-butyl thiazol-4-yl((2,3,4-trifluorophenyl)sulfonyl)carbamate

Guidance literature:: thiazol-4-ylaminocarboxylic acid tert-butyl ester; With lithium hexamethyldisilazane; In tetrahydrofuran; at -50 - 20 ℃; for 0.5h;

2,3,4-trifluorobenzenesulfonyl chloride; In tetrahydrofuran; at -78 - 20 ℃; for 16h;