(3,4-Dimethoxyphenyl)(4-fluorophenyl)methanone

Base Information

• Chemical Name: (3,4-Dimethoxyphenyl)(4-fluorophenyl)methanone
• CAS No.: 71186-85-1
• Molecular Formula: C15H13FO3
• Molecular Weight: 260.265
• DSSTox Substance ID: DTXSID60454383
• Wikidata: Q82275881
• Mol file: 71186-85-1.mol

Synonyms:(3,4-dimethoxyphenyl)(4-fluorophenyl)methanone;71186-85-1;3,4-dimethoxy-4'-fluorobenzophenone;(3,4-dimethoxyphenyl)-(4-fluorophenyl)methanone;SCHEMBL3973496;DTXSID60454383;ZAWIHPQSOJGMOW-UHFFFAOYSA-N;STK271159;3,4-Dimethoxy-4'-fluoro-benzophenone;AKOS005216391;CS-0357177

Chemical Property of (3,4-Dimethoxyphenyl)(4-fluorophenyl)methanone

Chemical Property:

• PSA: 35.53000
• LogP: 3.07390
• Storage Temp.: 2-8°C
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 260.08487243
• Heavy Atom Count: 19
• Complexity: 300

Purity/Quality:

99% ^*data from raw suppliers

(3,4-dimethoxyphenyl)(4-fluorophenyl)methanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C(=O)C2=CC=C(C=C2)F)OC

Technology Process of (3,4-Dimethoxyphenyl)(4-fluorophenyl)methanone

There total 5 articles about (3,4-Dimethoxyphenyl)(4-fluorophenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N,N-di-Boc-4-fluorobenzamide + 3,4-Dimethoxyphenylboronic acid (122775-35-3) → 3,4-Dimethoxy-4'-fluoro-benzophenone (71186-85-1)

Guidance literature:

With (3-phenylallyl)(chloro)-[1,3-bis(2,6-diisopropylphenyl)-4,5-dihydroimidazol-2-ylidene]palladium(II); water; potassium carbonate; In 2-methyltetrahydrofuran; at 20 ℃; for 15h; chemoselective reaction; Inert atmosphere; Schlenk technique; Green chemistry;

DOI:10.1002/adsc.201901188

Reference yield: 38.0%

4-Bromoveratrole (2859-78-1) + acetophenone (98-86-2) + 1-Bromo-4-fluorobenzene (460-00-4) → bis(3,4-dimethoxyphenyl)methanone (4131-03-7) + 3,4-Dimethoxy-4'-fluoro-benzophenone (71186-85-1) + 4,4'-Difluorobenzophenone (345-92-6)

Guidance literature:

4-Bromoveratrole; acetophenone; 1-Bromo-4-fluorobenzene; With palladium diacetate; caesium carbonate; triphenylphosphine; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere; Schlenk technique;

With oxygen; In N,N-dimethyl-formamide; at 0.153 - 20 ℃; Schlenk technique;

DOI:10.1021/jo5010185

Reference yield:

1,2-dimethoxybenzene (91-16-7) + 4-fluorobenzoyl chloride (403-43-0) → 3,4-Dimethoxy-4'-fluoro-benzophenone (71186-85-1)

Guidance literature:

aluminium trichloride;

upstream raw materials:

1,2-dimethoxybenzene

4-fluorobenzoyl chloride

4-Fluorobenzoic acid

4-Bromoveratrole

Downstream raw materials:

3-(3,4-Dimethoxyphenyl)-3-(4'-fluorophenyl)acrylonitrile

(3,4-dimethoxyphenyl)(4-fluorophenyl)methanone oxime

isopropyl((2S)-1-(((3,4-dimethoxylphenyl)(4-fluorophenyl)methyl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

(3,4-dimethoxyphenyl)(4-fluorophenyl)methanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 71186-85-1 3,4-diMethoxy-4'-Fluorobenzophenone

Send

Send

Metric Ton KG G Pound L ML

Send

Send