2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide

Base Information

Chemical Name:2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide
CAS No.:1073354-10-5
Molecular Formula:C17H26BNO3
Molecular Weight:303.209
Hs Code.:2934999090
DSSTox Substance ID:DTXSID50592127
Nikkaji Number:J3.001.508H
Wikidata:Q82486060
Mol file:1073354-10-5.mol

Synonyms:1073354-10-5;2-(TERT-BUTYLCARBONYLAMINO)PHENYLBORONIC ACID, PINACOL ESTER;2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide;N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pivalamide;2-(Tert-butylcarbonylamino)phenylboronic acid pinacol ester;MFCD05663849;DTXSID50592127;YSB35410;AKOS015960169;N-(2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl)pivalamide;AB21946;AT23180;AS-72174;SY331357;2-Pivalamidophenylboronic Acid Pinacol Ester;CS-0175356;J-001821;2-(tert-Butylcarbonylamino)phenylboronic acid, pinacol ester, AldrichCPR

Suppliers and Price of 2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(tert-Butylcarbonylamino)phenylboronicAcidPinacolEster
100mg
$ 60.00

Crysdot
N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pivalamide 95+%
5g
$ 392.00

Chemenu
N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pivalamide 95%
5g
$ 262.00

Chemenu
N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pivalamide 95%
1g
$ 74.00

Chemenu
N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pivalamide 95%
25g
$ 673.00

AOBChem
2-(Tert-butylcarbonylamino)phenylboronicacidpinacolester 97%
100g
$ 1500.00

American Custom Chemicals Corporation
2-(TERT-BUTYLCARBONYLAMINO)PHENYLBORONIC ACID PINACOL ESTER 95.00%
1G
$ 329.70

Alichem
N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pivalamide
5g
$ 400.00

Total 9 raw suppliers

Chemical Property of 2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide

Chemical Property:

PSA：47.56000
LogP:3.04340
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:303.2005739
Heavy Atom Count:22
Complexity:412

Purity/Quality:

97% ^*data from raw suppliers

2-(tert-Butylcarbonylamino)phenylboronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC=CC=C2NC(=O)C(C)(C)C

Technology Process of 2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide

There total 3 articles about 2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 76-09-5
2,3-dimethyl-2,3-butane diol

: 6625-74-7
N-pivaloylaniline

: 10294-33-4
boron tribromide

: 1073354-10-5
2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propionamide

Guidance literature:: N-pivaloylaniline; boron tribromide; In 1,2-dichloro-ethane; at 25 ℃; for 1h; Schlenk technique; Inert atmosphere;

2,3-dimethyl-2,3-butane diol; With potassium carbonate; In water; 1,2-dichloro-ethane; for 1h; Schlenk technique; Inert atmosphere;

Reference yield: 85.0%

: 62662-74-2
N-(2-chlorophenyl)-2,2,2-trimethylacetamide

: 73183-34-3
bis(pinacol)diborane

: 1073354-10-5
2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propionamide

Guidance literature:: With tris(trimethylphosphine)nickel(II) chloride; (2,2,2-trifluoroethoxy)trimethylsilane; cesium fluoride; In 1,4-dioxane; at 100 ℃; for 12h; Inert atmosphere;
DOI:10.1021/ol202267t

Reference yield: 72.0%

: 6625-74-7
N-pivaloylaniline

: 73183-34-3
bis(pinacol)diborane

: 1073354-10-5
2,2-dimethyl-N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propionamide

Guidance literature:: bis(pinacol)diborane; With 5-methyl-2-(thiophen-3-yl)pyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; In tetrahydrofuran; at 20 ℃; for 0.0333333h; Inert atmosphere; Glovebox;

N-pivaloylaniline; In tetrahydrofuran; at 80 ℃; for 24h; regioselective reaction; Inert atmosphere; Sealed tube;
DOI:10.1021/jacs.0c13415