7-BroMo-2,3-dihydro-1,4-benzoxazepin-5(4H)-one

Base Information

• Chemical Name: 7-BroMo-2,3-dihydro-1,4-benzoxazepin-5(4H)-one
• CAS No.: 5755-05-5
• Molecular Formula: C9H8BrNO2
• Molecular Weight: 242.072
• Mol file: 5755-05-5.mol

Synonyms:7-Brom-5-oxo-2,3,4,5-tetrahydro-1,4-benzoxazepin;RW2677;7-Brom-2,3-dihydro-4H-<1.4>benzoxazepin-5-on;

Chemical Property of 7-BroMo-2,3-dihydro-1,4-benzoxazepin-5(4H)-one

Chemical Property:

• Appearance/Colour: white powder
• PSA: 41.82000
• LogP: 1.58170
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

7-Bromo-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-BroMo-2,3-dihydro-1,4-benzoxazepin-5(4H)-one

There total 17 articles about 7-BroMo-2,3-dihydro-1,4-benzoxazepin-5(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2,3-dihydro-1,4-benzoxazepin-5(4H)-one (703-51-5) → 7-bromo-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (5755-05-5)

Guidance literature:

With bromine; In acetic acid;

Reference yield: 82.0%

C18H14BrNO5 + methylamine (74-89-5) → C19H19BrN2O5 + C18H16BrNO6 + 7-bromo-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (5755-05-5)

Guidance literature:

With water; In ethanol; at 85 ℃;

Reference yield: 67.0%

6-bromochroman-4-one (49660-57-3) → 7-bromo-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (5755-05-5)

Guidance literature:

6-bromochroman-4-one; With sodium azide; In benzene; at 0 ℃;

With sulfuric acid; In benzene; at 5 - 20 ℃;

upstream raw materials:

6-bromochroman-4-one

2,3-dihydro-1,4-benzoxazepin-5(4H)-one

methyl 5-bromo-2-{[2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)ethyl]oxy}benzoate

5-bromo-2-hydroxy-benzoic acid methyl ester

Downstream raw materials:

7-bromo-2,3,4,5-tetrahydrobenzo[f ][1,4]oxazepine hydrochloride

10-(4-(trifluoromethyl)phenyl)-5,6-dihydrobenzo[f][1,2,4]triazolo[4,3-d][1,4]oxazepine

7-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2,3,4,5-tetrahydro-1,4-benzoxazepine hydrochloride

2-[(1-methylethyl)oxy]-5-[3-(2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)-1,2,4-oxadiazol-5-yl]benzonitrile hydrochloride