1-(4-BROMO-2-FLUOROPHENYL)CYCLOPROPAN-1-OL

Base Information

Chemical Name:1-(4-BROMO-2-FLUOROPHENYL)CYCLOPROPAN-1-OL
CAS No.:1250254-02-4
Molecular Formula:C9H8BrFO
Molecular Weight:231.064
Hs Code.:
Mol file:1250254-02-4.mol

Synonyms:1-(4-BROMO-2-FLUOROPHENYL)CYCLOPROPAN-1-OL;1-(4-Bromo-2-fluorophenyl)cyclopropanol

Suppliers and Price of 1-(4-BROMO-2-FLUOROPHENYL)CYCLOPROPAN-1-OL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 1-(4-BROMO-2-FLUOROPHENYL)CYCLOPROPAN-1-OL

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(4-BROMO-2-FLUOROPHENYL)CYCLOPROPAN-1-OL

There total 2 articles about 1-(4-BROMO-2-FLUOROPHENYL)CYCLOPROPAN-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 10467-10-4
ethylmagnesium iodide

: 179232-29-2
methyl 4-bromo-2-fluorobenzoate

: 1250254-02-4
1-(4-bromo-2-fluorophenyl)cyclopropanol

Guidance literature:: ethylmagnesium iodide; With titanium(IV) isopropylate; In diethyl ether; at -78 ℃; for 2.25h;

methyl 4-bromo-2-fluorobenzoate; In diethyl ether; at -78 - 23 ℃; for 16h;

Reference yield:

: 112704-79-7
2-fluoro-4-bromobenzoic acid

: 1250254-02-4
1-(4-bromo-2-fluorophenyl)cyclopropanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: thionyl chloride / 12.25 h / 0 - 23 °C

2.1: titanium(IV) isopropylate / diethyl ether / 2.25 h / -78 °C

2.2: 16 h / -78 - 23 °C

With titanium(IV) isopropylate; thionyl chloride; In diethyl ether;