(4R)-3-((2S,3S)-2-Hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenyl-butyryl)-5,5 dimethyl-thiazolidine-4-carboxylic acid allylamide

Base Information

Chemical Name:(4R)-3-((2S,3S)-2-Hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenyl-butyryl)-5,5 dimethyl-thiazolidine-4-carboxylic acid allylamide
CAS No.:478410-84-3
Molecular Formula:C₂₇H₃₃N₃O₅S
Molecular Weight:511.642
Hs Code.:
UNII:USI577N9VE
ChEMBL ID:CHEMBL577569
DSSTox Substance ID:DTXSID90460038
Wikidata:Q76416859

(4R)-3-((2S,3S)-2-Hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenyl-butyryl)-5,5 dimethyl-thiazolidine-4-carboxylic acid allylamide

Synonyms:478410-84-3;AG-1859;UNII-USI577N9VE;KNI-1317;USI577N9VE;AG-001859;AG 1859;AG 001859;(4R)-3-((2S,3S)-2-Hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenyl-butyryl)-5,5 dimethyl-thiazolidine-4-carboxylic acid allylamide;(4R)-3-[(2S,3S)-2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL-BUTYRYL]-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID ALLYLAMIDE;(4R)-3-((2S,3S)-2-Hydroxy-3-((3-hydroxy-2-methylbenzoyl)amino)-1-oxo-4-phenylbutyl)-5,5-dimethyl-N-2-propenyl-4-thiazolidinecarboxamide;(4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl]-5,5-dimethyl-N-prop-2-enyl-1,3-thiazolidine-4-carboxamide;(R)-N-allyl-3-((2S,3S)-2-hydroxy-3-(3-hydroxy-2-methylbenzamido)-4-phenylbutanoyl)-5,5-dimethylthiazolidine-4-carboxamide;LXRNKYYBEZMYNM-ACIOBRDBSA-N;CHEMBL577569;SCHEMBL1055412;DTXSID90460038;AKOS040747774;PD161277;(4R)-N-allyl-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methyl-benzoyl)amino]-4-phenyl-butanoyl]-5,5-dimethyl-thiazolidine-4-carboxamide;4-Thiazolidinecarboxamide, 3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-1-oxo-4-phenylbutyl]-5,5-dimethyl-N-2-propenyl-, (4R)-

Suppliers and Price of (4R)-3-((2S,3S)-2-Hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenyl-butyryl)-5,5 dimethyl-thiazolidine-4-carboxylic acid allylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4R)-3-((2S,3S)-2-Hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenyl-butyryl)-5,5 dimethyl-thiazolidine-4-carboxylic acid allylamide

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:511.21409234
Heavy Atom Count:36
Complexity:800

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC=C1O)C(=O)NC(CC2=CC=CC=C2)C(C(=O)N3CSC(C3C(=O)NCC=C)(C)C)O
Isomeric SMILES:CC1=C(C=CC=C1O)C(=O)N[C@@H](CC2=CC=CC=C2)[C@@H](C(=O)N3CSC([C@H]3C(=O)NCC=C)(C)C)O

Technology Process of (4R)-3-((2S,3S)-2-Hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenyl-butyryl)-5,5 dimethyl-thiazolidine-4-carboxylic acid allylamide

There total 4 articles about (4R)-3-((2S,3S)-2-Hydroxy-3-(3-hydroxy-2-methylbenzoylamino)-4-phenyl-butyryl)-5,5 dimethyl-thiazolidine-4-carboxylic acid allylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: acetic acid 3-{(1S,2S)-3-[(4R)-4-allylcarbamoyl-5,5-dimethyl-thiazolidin-3-yl]-1-benzyl-2-hydroxy-3-oxo-propylcarbamoyl}-2-methyl-phenyl ester

: 478410-84-3
KNI-1317

Guidance literature:: With methanol; potassium carbonate; In 2-methyltetrahydrofuran; at 20 ℃; for 5.5h; Product distribution / selectivity;

Reference yield:

: 96-47-9
2-methyltetrahydrofuran

: 478411-22-2
(2S,3S)-3-(3-Acetoxy-2-methyl-benzoylamino)-2-hydroxy-4-phenyl-butyric acid

: i-PrOAc

: acetic acid 3-{(1S,2S)-3-[(4R)-4-allylcarbamoyl-5,5-dimethyl-thiazolidin-3-yl]-1-benzyl-2-hydroxy-3-oxo-propylcarbamoyl}-2-methyl-phenyl ester

: 478410-84-3
KNI-1317

Guidance literature:: With magnesium sulfate; potassium carbonate; sodium chloride; In methanol; water;

Reference yield:

: 749905-01-9
(2S,3S)-2-Acetoxy-3-(3-acetoxy-2-methyl-benzoylamino)-4-phenyl-butyric acid

: 1026299-75-1
(2S,3S)-2-acetoxy-3-(3-acetoxy-2-methyl-benzoylamino)-4-phenyl-butyric acid chloride

: 749905-00-8
(R)-5,5-Dimethyl-thiazolidine-4-carboxylic acid allylamide hydrochloride

: 478410-84-3
KNI-1317

Guidance literature:: With pyridine; hydrogenchloride; potassium hydroxide; thionyl chloride; In methanol; n-heptane; water; ethyl acetate; acetonitrile;