2-Propanol, 1-[(4-aMino-2-broMo-5-fluorophenyl)aMino]-3-(phenylMethoxy)-, (2R)-

Base Information

Chemical Name:2-Propanol, 1-[(4-aMino-2-broMo-5-fluorophenyl)aMino]-3-(phenylMethoxy)-, (2R)-
CAS No.:1294504-63-4
Molecular Formula:C16H18BrFN2O2
Molecular Weight:369.234
Hs Code.:

Synonyms:2-Propanol, 1-[(4-aMino-2-broMo-5-fluorophenyl)aMino]-3-(phenylMethoxy)-, (2R)-;2-Propanol, 1-[(4-aMino-2-broMo-5-fluorophenyl)aMino]-3-(phenylMethoxy)-, (2R)-5;(R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol

Suppliers and Price of 2-Propanol, 1-[(4-aMino-2-broMo-5-fluorophenyl)aMino]-3-(phenylMethoxy)-, (2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 4 raw suppliers

Chemical Property of 2-Propanol, 1-[(4-aMino-2-broMo-5-fluorophenyl)aMino]-3-(phenylMethoxy)-, (2R)-

Chemical Property:

PSA：67.51000
LogP:3.81420

Purity/Quality:: 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Propanol, 1-[(4-aMino-2-broMo-5-fluorophenyl)aMino]-3-(phenylMethoxy)-, (2R)-

There total 5 articles about 2-Propanol, 1-[(4-aMino-2-broMo-5-fluorophenyl)aMino]-3-(phenylMethoxy)-, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1342896-73-4
(R)-1-(benzyloxy)-3-(2-bromo-5-fluoro-4-nitrophenylamino)propan-2-ol

: 1294504-63-4
(R)-1-(4-amino-2-bromo-5-fluorophenylamino)-3-(benzyloxy)propan-2-ol

Guidance literature:: With platinum on carbon; hydrogen; In Isopropyl acetate; at 20 ℃; for 17.5h; under 2585.81 Torr;

Reference yield:

: 1294504-64-5
(R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt

: 1294504-63-4
(R)-1-(4-amino-2-bromo-5-fluorophenylamino)-3-(benzyloxy)propan-2-ol

Guidance literature:: With sodium hydrogencarbonate; In ethyl acetate;

Reference yield:

: 2369-13-3
3-fluoro-4-nitroaniline

: 1294504-63-4
(R)-1-(4-amino-2-bromo-5-fluorophenylamino)-3-(benzyloxy)propan-2-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid; bromine / chloroform / 2.33 h / 0 °C

2.1: zinc(II) perchlorate / toluene / 2 h / 20 °C / Molecular sieve; Inert atmosphere

2.2: 15 h / 85 °C / Molecular sieve; Inert atmosphere

3.1: ammonium chloride; zinc / water; ethanol / 4 h / 85 °C

With zinc(II) perchlorate; bromine; ammonium chloride; acetic acid; zinc; In ethanol; chloroform; water; toluene;