(R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt

Base Information

Chemical Name:(R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt
CAS No.:1294504-64-5
Molecular Formula:C₇H₈O₃S*C₁₆H₁₈BrFN₂O₂
Molecular Weight:541.438
Hs Code.:

Synonyms:(R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt

Suppliers and Price of (R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 10 raw suppliers

Chemical Property of (R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt

Chemical Property:

Purity/Quality:: 99.9% ^*data from raw suppliers

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Technology Process of (R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt

There total 6 articles about (R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1294504-63-4
(R)-1-(4-amino-2-bromo-5-fluorophenylamino)-3-(benzyloxy)propan-2-ol

: 104-15-4
toluene-4-sulfonic acid

: 1294504-64-5
(R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt

Guidance literature:: In dichloromethane; at 20 ℃; for 16h;

Reference yield:

: 952664-69-6
2-bromo-5-fluoro-4-nitroaniline

: 104-15-4
toluene-4-sulfonic acid

: 14618-80-5
(R)-benzyl glycidol

: 1294504-64-5
(R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt

Guidance literature:: 2-bromo-5-fluoro-4-nitroaniline; (R)-benzyl glycidol; Zn(ClO₄)₂·2H₂O; In toluene; at 20 - 80 ℃; Molecular sieve;

With hydrogen; platinum on carbon; In toluene; at 30 ℃; under 750.075 Torr;

toluene-4-sulfonic acid; In dichloromethane;

Reference yield:

: 1342896-73-4
(R)-1-(benzyloxy)-3-(2-bromo-5-fluoro-4-nitrophenylamino)propan-2-ol

: 104-15-4
toluene-4-sulfonic acid

: 1294504-64-5
(R)-1-((4-amino-2-bromo-5-fluorophenyl)amino)-3-(benzyloxy)propan-2-ol p-toluenesulfonic acid salt

Guidance literature:: (R)-1-(benzyloxy)-3-(2-bromo-5-fluoro-4-nitrophenylamino)propan-2-ol; With hydrogen; In Isopropyl acetate; at 30 ℃; under 750.075 Torr; Inert atmosphere; Molecular sieve;

toluene-4-sulfonic acid; In dichloromethane;