MS417

Base Information

Chemical Name:MS417
CAS No.:916489-36-6
Molecular Formula:C20H19ClN4O2S
Molecular Weight:414.915
Hs Code.:
Mol file:916489-36-6.mol

Synonyms:MS417;(S)-methyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

Suppliers and Price of MS417

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
MS417 ≥98% (HPLC)
5mg
$ 103.00

Sigma-Aldrich
MS417 ≥98% (HPLC)
25mg
$ 414.00

DC Chemicals
MS417 >98%
1 g
$ 2500.00

ChemScene
MS417 99.51%
250mg
$ 1300.00

ChemScene
MS417 99.51%
100mg
$ 700.00

ChemScene
MS417 99.51%
50mg
$ 420.00

ChemScene
MS417 99.51%
10mg
$ 160.00

ChemScene
MS417 99.51%
5mg
$ 100.00

Total 11 raw suppliers

Chemical Property of MS417

Chemical Property:

Boiling Point:596.8±60.0 °C(Predicted)
PKA:1.86±0.60(Predicted)
PSA：97.61000
Density:1.43±0.1 g/cm3(Predicted)
LogP:3.79820

Purity/Quality:

99%, ^*data from raw suppliers

MS417 ≥98% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of MS417

There total 3 articles about MS417 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 67-56-1
methanol

: 1268524-70-4
(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate

: 916489-36-6
methyl 2-((6S,Z)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f] [1,2,4]triazolo[4,3-a] [1,4]diazepin-6-yl)acetate

Guidance literature:: With sulfuric acid; Reflux;

Reference yield: 58.0%

: 202592-23-2
(S)-[4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid

: 124-41-4
sodium methylate

: 916489-36-6
methyl 2-((6S,Z)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f] [1,2,4]triazolo[4,3-a] [1,4]diazepin-6-yl)acetate

Guidance literature:: (S)-[4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid; With pivaloyl chloride; triethylamine; In tetrahydrofuran; at -30 - 0 ℃; for 0.666667h;

sodium methylate; In tetrahydrofuran; methanol; at -30 - 20 ℃; for 1.16667h;
DOI:10.1016/j.bmcl.2016.01.084

Reference yield:

: 67-56-1
methanol

: 202592-23-2
(S)-[4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid

: 916489-36-6
methyl 2-((6S,Z)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f] [1,2,4]triazolo[4,3-a] [1,4]diazepin-6-yl)acetate

Guidance literature:: methanol; (S)-[4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid; With thionyl chloride; at 0 - 20 ℃; for 5h;

With sodium hydrogencarbonate; In chloroform; water;