1-[2-[Bis(isopropyl)phosphino]phenyl]-3,5-diphenyl-1H-pyrazole

Base Information

Chemical Name:1-[2-[Bis(isopropyl)phosphino]phenyl]-3,5-diphenyl-1H-pyrazole
CAS No.:628333-84-6
Molecular Formula:C₂₇H₂₉N₂P
Molecular Weight:412.514
Hs Code.:
DSSTox Substance ID:DTXSID00698042
Nikkaji Number:J1.937.227H
Mol file:628333-84-6.mol

Synonyms:628333-84-6;1-[2-[BIS(ISOPROPYL)PHOSPHINO]PHENYL]-3,5-DIPHENYL-1H-PYRAZOLE;TRIPPYPHOS-2;DTXSID00698042;FT-0728049;[2-(3,5-Diphenyl-1H-pyrazole-1-yl)phenyl]diisopropylphosphine;1-{2-[Di(propan-2-yl)phosphanyl]phenyl}-3,5-diphenyl-1H-pyrazole

Suppliers and Price of 1-[2-[Bis(isopropyl)phosphino]phenyl]-3,5-diphenyl-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-[2-[BIS(ISOPROPYL)PHOSPHINO]PHENYL]-3,5-DIPHENYL-1H-PYRAZOLE 95.00%
5MG
$ 503.99

Total 3 raw suppliers

Chemical Property of 1-[2-[Bis(isopropyl)phosphino]phenyl]-3,5-diphenyl-1H-pyrazole

Chemical Property:

PSA：31.41000
LogP:7.13030
XLogP3:6.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:412.20683593
Heavy Atom Count:30
Complexity:501

Purity/Quality:

95% ^*data from raw suppliers

1-[2-[BIS(ISOPROPYL)PHOSPHINO]PHENYL]-3,5-DIPHENYL-1H-PYRAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)P(C1=CC=CC=C1N2C(=CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4)C(C)C

Technology Process of 1-[2-[Bis(isopropyl)phosphino]phenyl]-3,5-diphenyl-1H-pyrazole

There total 3 articles about 1-[2-[Bis(isopropyl)phosphino]phenyl]-3,5-diphenyl-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 40244-90-4
Chlorodiisopropylphosphane

: 2183-27-9
1,3,5-triphenyl-1H-pyrazole

: 628333-84-6
1-(2-di-isopropylphosphinophenyl)-3,5-diphenyl-1H-pyrazole

Guidance literature:: 1,3,5-triphenyl-1H-pyrazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 1.33333h;

Chlorodiisopropylphosphane; In tetrahydrofuran; hexane; at 0 - 20 ℃;
DOI:10.1055/s-2003-40881

Reference yield:

: 120-46-7,61346-73-4
1,3-diphenylpropanedione

: 628333-84-6
1-(2-di-isopropylphosphinophenyl)-3,5-diphenyl-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: 96 percent / AcOH / propan-2-ol / 8 h / 80 °C

2.1: n-BuLi / tetrahydrofuran; hexane / 1.33 h / -78 - 0 °C

2.2: 86 percent / tetrahydrofuran; hexane / 0 - 20 °C

With n-butyllithium; acetic acid; In tetrahydrofuran; hexane; isopropyl alcohol;
DOI:10.1055/s-2003-40881

Reference yield:

: 100-63-0
phenylhydrazine

: 628333-84-6
1-(2-di-isopropylphosphinophenyl)-3,5-diphenyl-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: 96 percent / AcOH / propan-2-ol / 8 h / 80 °C

2.1: n-BuLi / tetrahydrofuran; hexane / 1.33 h / -78 - 0 °C

2.2: 86 percent / tetrahydrofuran; hexane / 0 - 20 °C

With n-butyllithium; acetic acid; In tetrahydrofuran; hexane; isopropyl alcohol;
DOI:10.1055/s-2003-40881