4-Amino-3-chloro-N,N-dimethylbenzamide

Base Information

Chemical Name:4-Amino-3-chloro-N,N-dimethylbenzamide
CAS No.:1019018-13-3
Molecular Formula:C₉H₁₁ClN₂O
Molecular Weight:198.652
Hs Code.:
DSSTox Substance ID:DTXSID40604667
Wikidata:Q82502670
Mol file:1019018-13-3.mol

Synonyms:4-Amino-3-chloro-N,N-dimethylbenzamide;1019018-13-3;Benzamide, 4-amino-3-chloro-N,N-dimethyl-;SCHEMBL357230;DTXSID40604667;NQQURCVYDZGIKC-UHFFFAOYSA-N;AKOS006314202;AM807389

Suppliers and Price of 4-Amino-3-chloro-N,N-dimethylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Amino-3-chloro-N,N-dimethylbenzamide

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:198.0559907
Heavy Atom Count:13
Complexity:196

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C1=CC(=C(C=C1)N)Cl

Technology Process of 4-Amino-3-chloro-N,N-dimethylbenzamide

There total 3 articles about 4-Amino-3-chloro-N,N-dimethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1019018-13-3
4-amino-3-chloro-N,N-dimethylbenzamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In tetrahydrofuran; for 18h;

Reference yield: 89.0%

: 2486-71-7
4-amino-3-chlorobenzoic acid

: 506-59-2
N,N-dimethylammonium chloride

: 1019018-13-3
4-amino-3-chloro-N,N-dimethylbenzamide

Guidance literature:: N,N-dimethylammonium chloride; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 0.5h;

4-amino-3-chlorobenzoic acid; With HATU; In tetrahydrofuran; for 1.5h;

Reference yield: 16.0%

: 16761-18-5
4-acetamido-3-chlorobenzenesulphonyl chloride

: 124-40-3
dimethyl amine

: 1019018-13-3
4-amino-3-chloro-N,N-dimethylbenzamide

Guidance literature:: 4-acetamido-3-chlorobenzenesulphonyl chloride; dimethyl amine; In methanol; at 20 ℃; for 2.5h; Inert atmosphere;

With hydrogenchloride; In methanol; for 6h; Reflux; Inert atmosphere;
DOI:10.1021/jm401395s