Tert-butyl 3-phenylpiperidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 3-phenylpiperidine-1-carboxylate
CAS No.:1056971-32-4
Molecular Formula:C16H23NO2
Molecular Weight:261.364
Hs Code.:
Nikkaji Number:J3.224.894B
Mol file:1056971-32-4.mol

Synonyms:tert-butyl 3-phenylpiperidine-1-carboxylate;1056971-32-4;SCHEMBL6359096;AKOS024627904;1-(tert-Butoxycarbonyl)-3-phenylpiperidine;F2167-1119

Suppliers and Price of Tert-butyl 3-phenylpiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Tert-butyl 3-phenylpiperidine-1-carboxylate

Chemical Property:

Melting Point:71 °C
PSA：29.54000
LogP:3.73900
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:261.172878976
Heavy Atom Count:19
Complexity:302

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCC(C1)C2=CC=CC=C2

Technology Process of Tert-butyl 3-phenylpiperidine-1-carboxylate

There total 9 articles about Tert-butyl 3-phenylpiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 3973-62-4
3-phenylpiperidine

: 24424-99-5
di-tert-butyl dicarbonate

: 1056971-32-4
tert-butyl-3-phenylpiperidine-1-carboxylate

Guidance literature:: With trimethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 4h; Inert atmosphere;
DOI:10.3762/bjoc.14.100

Reference yield: 90.0%

: 3973-62-4
3-phenylpiperidine

: 201230-82-2
carbon monoxide

: 75-65-0
tert-butyl alcohol

: 1056971-32-4
tert-butyl-3-phenylpiperidine-1-carboxylate

Guidance literature:: With gold(III) chloride; copper(l) iodide; at 50 ℃; for 24h; under 750.075 - 3000.3 Torr;
DOI:10.1002/cssc.202102400

Reference yield: 88.0%

: 850761-36-3,1354004-63-9,1354010-37-9
tert-butyl 3-iodo-1-piperidinecarboxylate

: 100-58-3
phenylmagnesium bromide

: 1056971-32-4
tert-butyl-3-phenylpiperidine-1-carboxylate

Guidance literature:: With (1R,2R)-bis(dimethylamino)cyclohexane; cobalt(II) chloride; In tetrahydrofuran; at -10 ℃; for 3h; Inert atmosphere;
DOI:10.1002/chem.201501543