N-(4,6-dichloro-2-(propylthio)pyriMidin-5-yl)forMaMide

Base Information

Chemical Name:N-(4,6-dichloro-2-(propylthio)pyriMidin-5-yl)forMaMide
CAS No.:1402150-28-0
Molecular Formula:C8H9Cl2N3OS
Molecular Weight:266.151
Hs Code.:
Mol file:1402150-28-0.mol

Synonyms:N-(4,6-dichloro-2-(propylthio)pyriMidin-5-yl)forMaMide;N-[4,6-dichloro-2-(propylthio)-5-pyrimidinyl]Formamide

Suppliers and Price of N-(4,6-dichloro-2-(propylthio)pyriMidin-5-yl)forMaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of N-(4,6-dichloro-2-(propylthio)pyriMidin-5-yl)forMaMide

Chemical Property:

Boiling Point:446.0±45.0 °C(Predicted)
PKA:10.80±0.70(Predicted)
PSA：80.18000
Density:1.45±0.1 g/cm3(Predicted)
LogP:3.56270

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(4,6-dichloro-2-(propylthio)pyriMidin-5-yl)forMaMide

There total 2 articles about N-(4,6-dichloro-2-(propylthio)pyriMidin-5-yl)forMaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 145783-15-9
4,6-dichloro-2-(propylsulfanyl)-5-pyrimidinamine

: 64-18-6
formic acid

: 1402150-28-0
N-[4,6-dichloro-2-(propylthio)pyrimidin-5-yl]formamide

Guidance literature:: With acetic anhydride; In toluene; at 0 - 20 ℃;

Reference yield:

: 145783-14-8
4,6-dichloro-5-nitro-2-(propylsulfanyl)pyrimidine

: 1402150-28-0
N-[4,6-dichloro-2-(propylthio)pyrimidin-5-yl]formamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; iron / methanol / 50 °C

2: acetic anhydride / toluene / 0 - 20 °C

With acetic anhydride; iron; acetic acid; In methanol; toluene;

Reference yield:

: 1402150-28-0
N-[4,6-dichloro-2-(propylthio)pyrimidin-5-yl]formamide

: 274693-27-5,2096989-55-6,2096989-56-7
ticagrelor

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / ethanol / 40 - 80 °C / Inert atmosphere

2: hydrogenchloride; water / methanol / 35 °C

3: sodium nitrite / water; methanol / 0 - 5 °C

4: N-ethyl-N,N-diisopropylamine / acetonitrile / 25 - 35 °C

With hydrogenchloride; water; triethylamine; N-ethyl-N,N-diisopropylamine; sodium nitrite; In methanol; ethanol; water; acetonitrile;