4-(Quinolin-4-yl)aniline

Base Information

Chemical Name:4-(Quinolin-4-yl)aniline
CAS No.:22191-98-6
Molecular Formula:C15H12N2
Molecular Weight:0
Hs Code.:2933499090
DSSTox Substance ID:DTXSID20702251
Nikkaji Number:J83.159J
Wikidata:Q82634106
Mol file:22191-98-6.mol

Synonyms:4-(Quinolin-4-yl)aniline;22191-98-6;4-(4-Aminophenyl)quinoline;4-quinolin-4-ylaniline;SCHEMBL3974248;DTXSID20702251;EN300-331852

Suppliers and Price of 4-(Quinolin-4-yl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
4-(Quinolin-4-yl)aniline
2.5g
$ 1837.00

AK Scientific
4-(Quinolin-4-yl)aniline
1g
$ 985.00

Total 1 raw suppliers

Chemical Property of 4-(Quinolin-4-yl)aniline

Chemical Property:

PSA：38.91000
LogP:4.06520
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:220.100048391
Heavy Atom Count:17
Complexity:245

Purity/Quality:: 4-(Quinolin-4-yl)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CC=N2)C3=CC=C(C=C3)N

Technology Process of 4-(Quinolin-4-yl)aniline

There total 5 articles about 4-(Quinolin-4-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-(4-nitrophenyl)quinoline

: 22191-98-6
4-(p-aminophenyl)-quinoline

Guidance literature:: With hydrogenchloride; tin(ll) chloride;

Reference yield:

: 19591-17-4
o-iodoacetanilide

: 22191-98-6
4-(p-aminophenyl)-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: diethylamine, CuI, bis(triphenylphosphine)palladium diacetate / dimethylformamide / 2 h / Ambient temperature

2: 1.) Pd(OAc)2, PPh₃, HCOOK, 2.) p-toluenosulfonic acid / 1.) DMF, 40 deg C, 4 h, 2.) EtOH, 70 deg C, 18 h

With palladium diacetate; copper(l) iodide; bis(acetato)bis(triphenylphosphine)palladium⁽⁰⁾; potassium formate; toluene-4-sulfonic acid; diethylamine; triphenylphosphine; In N,N-dimethyl-formamide;
DOI:10.1016/0040-4020(96)00557-1

Reference yield:

: 181420-00-8
N-[2-(3,3-Diethoxy-prop-1-ynyl)-phenyl]-acetamide

: 540-37-4
p-aminoiodobenzene

: 22191-98-6
4-(p-aminophenyl)-quinoline

: 104967-74-0
3-(p-aminophenyl)-quinoline

Guidance literature:: With palladium diacetate; potassium formate; toluene-4-sulfonic acid; triphenylphosphine; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) DMF, 40 deg C, 4 h, 2.) EtOH, 70 deg C, 18 h;
DOI:10.1016/0040-4020(96)00557-1