tert-butyl dimethylcarbamate

Base Information

• Chemical Name: tert-butyl dimethylcarbamate
• CAS No.: 7541-17-5
• Molecular Formula: C7H15 N O2
• Molecular Weight: 145.202
• Mol file: 7541-17-5.mol

Synonyms:Carbamicacid, dimethyl-, 1,1-dimethylethyl ester (9CI); Carbamic acid, dimethyl-,tert-butyl ester (8CI); NSC 223096; tert-Butyl N,N-dimethylcarbamate;tert-Butyl dimethylcarbamate

Chemical Property of tert-butyl dimethylcarbamate

Chemical Property:

• Vapor Pressure: 2.19mmHg at 25°C
• Boiling Point: 162.2°Cat760mmHg
• Flash Point: 51.9°C
• Density: 0.937g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-butyl dimethylcarbamate

There total 9 articles about tert-butyl dimethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

di-tert-butyl dicarbonate (24424-99-5) + dimethyl amine (124-40-3) → tert-butyl N,N-dimethylcarbamate (7541-17-5)

Guidance literature:

With 1-methylimidazolium tetrafluoroborate; at 30 - 35 ℃; for 0.0333333h;

DOI:10.1016/j.tetlet.2008.02.126

Reference yield: 82.0%

tert.-butylhydroperoxide (75-91-2) + N,N-dimethyl-formamide (68-12-2,33513-42-7) + benzylamine (100-46-9) → tert-butyl N,N-dimethylcarbamate (7541-17-5) + N,N-dimethylbenzamide (611-74-5)

Guidance literature:

With hydrogenchloride; iodine; In cyclohexane; water; at 70 - 80 ℃; for 20h;

DOI:10.1039/c4cc00621f

Reference yield: 82.0%

di-tert-butyl dicarbonate (24424-99-5) + N,N-dimethylammonium chloride (506-59-2) → tert-butyl N,N-dimethylcarbamate (7541-17-5)

Guidance literature:

With dmap; triethylamine; In dichloromethane; for 24h;

DOI:10.1021/jo970985b

upstream raw materials:

N,N-Dimethylcarbamoyl chloride

tert-butyl alcohol

tert-butyl phenyl carbonate

dimethyl amine

Downstream raw materials:

tert-butyl N-benzyl-N-methylcarbamate

(Z)-methyl 3-[[(1,1-dimethylethoxycarbonyl)methylamino]methyl]-3-phenyl-2-propenoate

carbamic acid, N-methyl-N-(3-butenyl), 1,1-dimethylethyl ester

tert-butyl ethyl(4-methoxybenzyl)carbamate

Refernces

• 1、 Tian, Hao,Xia, Qing,Wang, Qiang,Dong, Jianyang,Liu, Yuxiu,Wang, Qingmin. "Direct α-Monofluoroalkenylation of Heteroatomic Alkanes via a Combination of Photoredox Catalysis and Hydrogen-Atom-Transfer Catalysis". supporting information. p. 4585 - 4589. Retrieved 2019/06/17.
• 2、 Dong, Jianyang,Xia, Qing,Lv, Xueli,Yan, Changcun,Song, Hongjian,Liu, Yuxiu,Wang, Qingmin. "Photoredox-Mediated Direct Cross-Dehydrogenative Coupling of Heteroarenes and Amines". supporting information. p. 5661 - 5665. Retrieved 2018/09/21.