5-Chlorofuro[3,2-b]pyridine

Base Information

Chemical Name:5-Chlorofuro[3,2-b]pyridine
CAS No.:182691-76-5
Molecular Formula:C7H4ClNO
Molecular Weight:153.57
Hs Code.:2934999090
European Community (EC) Number:871-266-0
DSSTox Substance ID:DTXSID00442340
Mol file:182691-76-5.mol

Synonyms:5-Chlorofuro[3,2-b]pyridine;182691-76-5;Furo[3,2-b]pyridine, 5-chloro-;SCHEMBL5308681;AMY2124;DTXSID00442340;MFCD15143869;SB15844;AS-51045;CS-0054451;EN300-121951;P11783;W-206304

Suppliers and Price of 5-Chlorofuro[3,2-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-Chlorofuro[3,2-b]pyridine
500mg
$ 720.00

Matrix Scientific
5-Chlorofuro[3,2-b]pyridine
5g
$ 3150.00

Matrix Scientific
5-Chlorofuro[3,2-b]pyridine
1g
$ 1050.00

Crysdot
5-Chlorofuro[3,2-b]pyridine 97%
1g
$ 772.00

Biosynth Carbosynth
5-Chlorofuro[3,2-b]pyridine
1 g
$ 1345.00

Biosynth Carbosynth
5-Chlorofuro[3,2-b]pyridine
500 mg
$ 975.00

Biosynth Carbosynth
5-Chlorofuro[3,2-b]pyridine
100 mg
$ 310.00

Biosynth Carbosynth
5-Chlorofuro[3,2-b]pyridine
50 mg
$ 195.00

Biosynth Carbosynth
5-Chlorofuro[3,2-b]pyridine
250 mg
$ 610.00

American Custom Chemicals Corporation
5-CHLOROFURO[3,2-B]PYRIDINE 95.00%
5MG
$ 504.80

Total 10 raw suppliers

Chemical Property of 5-Chlorofuro[3,2-b]pyridine

Chemical Property:

Melting Point:50-53℃
Boiling Point:216.5±20.0 °C(Predicted)
PKA:-0.87±0.30(Predicted)
PSA：26.03000
Density:1.377±0.06 g/cm3(Predicted)
LogP:2.48120
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:152.9981414
Heavy Atom Count:10
Complexity:131

Purity/Quality:

NLT 98% ^*data from raw suppliers

5-Chlorofuro[3,2-b]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC2=C1OC=C2)Cl
Uses As a potent antiallergy agents.

Technology Process of 5-Chlorofuro[3,2-b]pyridine

There total 5 articles about 5-Chlorofuro[3,2-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 5-chloro-2-(trimethylsilyl)furo[3,2-b]pyridine

: 182691-76-5
5-chlorofuro[3,2-b]pyridine

Guidance literature:: With potassium fluoride; In methanol; at 25 - 60 ℃; for 15h; Inert atmosphere;

Reference yield: 47.0%

: 181526-18-1
4-oxidofuro[3,2-b]pyridin-4-ium

: 2-chlorofuro[3,2-b]pyridine

: 182691-76-5
5-chlorofuro[3,2-b]pyridine

: 182691-75-4
7-chlorofuro[3,2-b]pyridine

: 3-Chloro-furo[3,2-b]pyridine

Guidance literature:: With trichlorophosphate; In chloroform; for 1.5h; Heating;
DOI:10.1002/jhet.5570330409

Reference yield:

: 41288-96-4
6-chloropyridine-3-ol

: 182691-76-5
5-chlorofuro[3,2-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate; iodine / water / 2 h / 25 °C / Inert atmosphere

2: bis-triphenylphosphine-palladium(II) chloride; triethylamine; copper(l) iodide / 1,4-dioxane / 2.5 h / 45 °C / Inert atmosphere

3: potassium fluoride / methanol / 15 h / 25 - 60 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; potassium fluoride; copper(l) iodide; iodine; sodium carbonate; triethylamine; In 1,4-dioxane; methanol; water;