1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone

Base Information

Chemical Name:1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone
CAS No.:67589-15-5
Molecular Formula:C9H7F3O2
Molecular Weight:204.149
Hs Code.:2914790090
European Community (EC) Number:872-473-9
DSSTox Substance ID:DTXSID40472161
Wikidata:Q82300954
Mol file:67589-15-5.mol

Synonyms:1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone;67589-15-5;1-(2-HYDROXY-5-TRIFLUOROMETHYL-PHENYL)-ETHANONE;1-[2-hydroxy-5-(trifluoromethyl)phenyl]ethanone;MFCD11840324;1-(2-hydroxy-5-(trifluoromethyl)phenyl)ethan-1-one;1-[2-hydroxy-5-(trifluoromethyl)phenyl]ethan-1-one;2-hydroxy-5-(trifluoromethyl)acetophenone;SCHEMBL320481;DTXSID40472161;AKOS016006863;CS-W005903;SB38250;AM807412;DS-17299;SY113354;2'-hydroxy-5'-trifluoromethyl-acetophenone;1-(2-Hydroxy-5-trifluoromethyl-phenyl)ethanone;EN300-395555;F13146;A856480;2 inverted exclamation mark -Hydroxy-5 inverted exclamation mark -(trifluoromethyl)acetophenone

Suppliers and Price of 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Acetyl-4-(trifluoromethyl)phenol
100mg
$ 75.00

TRC
2-Acetyl-4-(trifluoromethyl)phenol
250mg
$ 165.00

Matrix Scientific
1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone 95+%
250mg
$ 252.00

Matrix Scientific
1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone 95+%
1g
$ 630.00

J&W Pharmlab
1-(2-Hydroxy-5-trifluoromethyl-phenyl)-ethanone 97%
1g
$ 128.00

J&W Pharmlab
1-(2-Hydroxy-5-trifluoromethyl-phenyl)-ethanone 97%
500mg
$ 98.00

J&W Pharmlab
1-(2-Hydroxy-5-trifluoromethyl-phenyl)-ethanone 97%
250mg
$ 88.00

J&W Pharmlab
1-(2-Hydroxy-5-trifluoromethyl-phenyl)-ethanone 97%
100mg
$ 78.00

J&W Pharmlab
1-(2-Hydroxy-5-trifluoromethyl-phenyl)-ethanone 97%
25g
$ 1552.00

J&W Pharmlab
1-(2-Hydroxy-5-trifluoromethyl-phenyl)-ethanone 97%
5g
$ 388.00

Total 22 raw suppliers

Chemical Property of 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone

Chemical Property:

Boiling Point:219.7±35.0 °C(Predicted)
PKA:8.76±0.18(Predicted)
PSA：37.30000
Density:1.335±0.06 g/cm3(Predicted)
LogP:2.61360
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:204.03981395
Heavy Atom Count:14
Complexity:225

Purity/Quality:

99%, ^*data from raw suppliers

2-Acetyl-4-(trifluoromethyl)phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C=CC(=C1)C(F)(F)F)O
Uses 2-Acetyl-4-(trifluoromethyl)phenol was used to study benzoxazepine-?based Orexin-?2 receptor antagonists.

Technology Process of 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone

There total 8 articles about 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 503464-99-1
1-(2-methoxy-5-(trifluoromethyl)phenyl)ethan-1-one

: 67589-15-5
1-(2-hydroxy-5-(trifluoromethyl)phenyl)ethan-1-one

Guidance literature:: With chloro-trimethyl-silane; sodium iodide; In acetonitrile; at -20 ℃; for 3h; Reflux;
DOI:10.1021/acs.jmedchem.7b00598