(3-IODO-4-METHOXYPHENYL)ACETIC ACID METHYL ESTER

Base Information

• Chemical Name: (3-IODO-4-METHOXYPHENYL)ACETIC ACID METHYL ESTER
• CAS No.: 124840-58-0
• Molecular Formula: C10H11IO3
• Molecular Weight: 306.1
• Mol file: 124840-58-0.mol

Synonyms:(3-IODO-4-METHOXYPHENYL)ACETIC ACID METHYL ESTER;methyl 2-(3-iodo-4-methoxyphenyl)acetate

Chemical Property of (3-IODO-4-METHOXYPHENYL)ACETIC ACID METHYL ESTER

Chemical Property:

• Boiling Point: 333.9±37.0 °C(Predicted)
• PSA: 35.53000
• Density: 1.625±0.06 g/cm3(Predicted)
• LogP: 2.01530

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3-IODO-4-METHOXYPHENYL)ACETIC ACID METHYL ESTER

There total 3 articles about (3-IODO-4-METHOXYPHENYL)ACETIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methanol (67-56-1) + 2-(3-iodo-4-methoxyphenyl)acetic acid (96122-61-1) → 3-Iod-4-methoxy-phenylessigsaeure-methylester (124840-58-0)

Guidance literature:

With sulfuric acid; In chloroform; for 16h; Heating;

DOI:10.1016/0040-4020(96)00937-4

Reference yield: 55.0%

[bis(acetoxy)iodo]benzene (3240-34-4) + 4-methoxy-phenyl acetic acid methyl ester (23786-14-3) → C10H10I2O3 (918658-20-5) + C12H13IO5 (918658-21-6) + 3-Iod-4-methoxy-phenylessigsaeure-methylester (124840-58-0)

Guidance literature:

With iodine; In dichloromethane; for 20h;

DOI:10.1016/j.bmcl.2006.08.111

Reference yield:

4-Methoxyphenylacetic acid (104-01-8) → 3-Iod-4-methoxy-phenylessigsaeure-methylester (124840-58-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / iodomonochlorid / 3 h

2: 93 percent / H₂SO₄ / CHCl₃ / 16 h / Heating

With sulfuric acid; Iodine monochloride; In chloroform;

DOI:10.1016/0040-4020(96)00937-4

upstream raw materials:

methanol

2-(3-iodo-4-methoxyphenyl)acetic acid

4-Methoxyphenylacetic acid

[bis(acetoxy)iodo]benzene

Downstream raw materials:

5,5'-Bis-<(methyloxycarbonyl)-methyl>-2,2'-dimethoxy-biphenyl

[4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid methyl ester

methyl 2-(3-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)-4,4-dimethylcyclohex-1-enyl)-4-methoxyphenyl)acetate

2-(3-(2-(((4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-4-methyl-2-oxooxazolidin-3-yl)methyl)-4,4-dimethylcyclohex-1-enyl)-4-methoxyphenyl)acetic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 124840-58-0 (3-IODO-4-METHOXYPHENYL)ACETIC ACID METHYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send