tert-Butyl (2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate

Base Information

Chemical Name:tert-Butyl (2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate
CAS No.:508223-54-9
Molecular Formula:C18H28BNO4
Molecular Weight:333.236
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30682353
Wikidata:Q82606693
Mol file:508223-54-9.mol

Synonyms:508223-54-9;4-(Boc-Amino)-3-methylphenylboronic acid, pinacol ester;tert-Butyl (2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate;tert-butyl N-[2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate;tert-butyl [2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate;SCHEMBL65546;DTXSID30682353;AEJFCKJZWOLDBF-UHFFFAOYSA-N;MFCD17214290;AKOS022184095;SB83338;BS-28575;CS-0136577;FT-0735894;EN300-316764;F76269;4-(Boc-Amino)-3-methylphenylboronic acid pinacol ester;4-(Boc-Amino)-3-methylphenylboronic acid,pinacol ester;tert-butyl N-[2-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate;tert-Butyl(2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate;[2-methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-carbamic acid tert-butyl ester;[2-methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]carbamic acid tert-butyl ester

Suppliers and Price of tert-Butyl (2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Boc-Amino)-3-methylphenylboronicacid,pinacolester
250mg
$ 140.00

Crysdot
tert-Butyl(2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate 95+%
1g
$ 475.00

Crysdot
tert-Butyl(2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate 95+%
5g
$ 1216.00

AK Scientific
4-(Boc-Amino)-3-methylphenylboronicacidpinacolester
5g
$ 1357.00

AK Scientific
4-(Boc-Amino)-3-methylphenylboronicacidpinacolester
1g
$ 477.00

Total 9 raw suppliers

Chemical Property of tert-Butyl (2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate

Chemical Property:

Boiling Point:395.5±42.0 °C(Predicted)
PKA:14.00±0.70(Predicted)
PSA：56.79000
Density:1.06±0.1 g/cm3(Predicted)
LogP:3.71420
Storage Temp.:Refrigerated.
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:333.2111385
Heavy Atom Count:24
Complexity:456

Purity/Quality:

97% ^*data from raw suppliers

4-(Boc-Amino)-3-methylphenylboronicacid,pinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC(=C(C=C2)NC(=O)OC(C)(C)C)C

Technology Process of tert-Butyl (2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate

There total 2 articles about tert-Butyl (2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 666746-27-6
(4-iodo-2-methyl-phenyl)-carbamic acid tert-butyl ester

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 508223-54-9
[2-methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]carbamic acid tert-butyl ester

Guidance literature:: With triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 80 ℃; for 4h;

Reference yield:

: 508223-54-9
[2-methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]carbamic acid tert-butyl ester

Guidance literature:

Reference yield: 96.0%

: 508223-54-9
[2-methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]carbamic acid tert-butyl ester

: 74-88-4
methyl iodide

: tert-butyl N-methyl-N-[2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate

Guidance literature:: [2-methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]carbamic acid tert-butyl ester; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.333333h; Inert atmosphere;

methyl iodide; In N,N-dimethyl-formamide; at 0 - 20 ℃;