N'-(naphthalen-2-yl)acetohydrazide

Base Information

• Chemical Name: N'-(naphthalen-2-yl)acetohydrazide
• CAS No.: 40880-56-6
• Molecular Formula: C12H12N2O
• Molecular Weight: 200.23648
• Mol file: 40880-56-6.mol

Synonyms:N'-(naphthalen-2-yl)acetohydrazide

Chemical Property of N'-(naphthalen-2-yl)acetohydrazide

Chemical Property:

• Melting Point: 169 - 171 °C
• PSA: 41.13000
• LogP: 2.76670

Purity/Quality:

99% ^*data from raw suppliers

N'-(Naphthalen-2-yl)acetohydrazide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N'-(naphthalen-2-yl)acetohydrazide

There total 4 articles about N'-(naphthalen-2-yl)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-naphthylhydrazine hydrochloride (2243-58-5) + acetic anhydride (108-24-7) → N′-(naphthalen-2-yl)acetohydrazide (40880-56-6)

Guidance literature:

2-naphthylhydrazine hydrochloride; With potassium carbonate; In water; at 20 ℃; for 0.25h;

acetic anhydride; In ethyl acetate; toluene; at 20 ℃; for 1h;

DOI:10.1021/jm3007323

Reference yield:

acetamide (60-35-5) + 2-hydrazinonaphthalene (2243-57-4) → N′-(naphthalen-2-yl)acetohydrazide (40880-56-6)

Guidance literature:

at 150 ℃;

Reference yield:

acetic anhydride (108-24-7) + 2-hydrazinonaphthalene (2243-57-4) → N′-(naphthalen-2-yl)acetohydrazide (40880-56-6)

Guidance literature:

upstream raw materials:

acetic anhydride

2-hydrazinonaphthalene

acetic acid

acetamide

Downstream raw materials:

4-{2-[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine

5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-ol

4-Nitro-2-carboxy-benzol-<1azo1>-2-<β-acetyl-hydrazino>-naphthalin

5-Nitro-4-methansulfon-phenol-(2azo1)-2-<β-acetyl-hydrazino>-naphthalin