Dimethylgermanium dichloride

Base Information

• Chemical Name: Dimethylgermanium dichloride
• CAS No.: 1529-48-2
• Molecular Formula: C2H6Cl2Ge
• Molecular Weight: 173.566
• Hs Code.: 29310099
• European Community (EC) Number: 216-216-5
• DSSTox Substance ID: DTXSID30165156
• Nikkaji Number: J47.005H
• Wikidata: Q15628298
• Mol file: 1529-48-2.mol

Synonyms:Dimethylgermanium dichloride;1529-48-2;Dichlorodimethylgermane;dichloro(dimethyl)germane;Germane, dichlorodimethyl-;Dimethyldichlorogermane;EINECS 216-216-5;Dimethylgermanedichloride;Dimethylgermyl dichloride;GeMe2Cl2;C2H6Cl2Ge;dimethyl-dichloro-germane;C2-H6-Cl2-Ge;Dimethyl germanium dichloride;SCHEMBL301599;DTXSID30165156;Dimethylgermanium dichloride, 99%;MFCD00013588;AKOS015916084;CS-0085905;FT-0694945;J-008965;Q15628298

Chemical Property of Dimethylgermanium dichloride

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Melting Point: -22 °C(lit.)
• Refractive Index: n20/D 1.46(lit.)
• Boiling Point: 122.999 °C at 760 mmHg
• Flash Point: 32.222 °C
• PSA: 0.00000
• Density: 1.505 g/mL at 25 °C(lit.)
• LogP: 2.16580
• Storage Temp.: Flammables area
• Sensitive.: Moisture Sensitive
• Water Solubility.: Hydrolyses in water.
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 173.9058333
• Heavy Atom Count: 5
• Complexity: 30.6

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dimethylgermanium dichloride, 99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 10-34
• Safety Statements: 16-26-27-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Ge](C)(Cl)Cl
• Uses: Dimethylgermanium dichloride is a useful organogermanium compound for synthesis and proteomics research. It is also used as an organic intermediate and in chemical research.

Technology Process of Dimethylgermanium dichloride

There total 40 articles about Dimethylgermanium dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

7,7-dimethyl-1,4,5,6-tetraphenyl-2,3-benzo-7-germanorbornadiene (76054-64-3) → Cl3CGe(CH3)2Cl (84174-04-9) + dichlorodimethylgermanium (1529-48-2)

Guidance literature:

In tetrachloromethane; byproducts: C2Cl6, 1,2,3,4-tetraphenylnaphtalene; 4 h., 70 °C.; 1,2,3,4-tetraphenylnaphtalene pptd. by EtOH, Me2GeCl2 and C2Cl6 are estimated by HPLC, Me2GeClCCl3 by NMR;

DOI:10.1021/ja00342a043

Reference yield: 93.0%

1,2-dichlorotetramethyldigermane (22702-77-8) + benzyl chloride (100-44-7) → benzoylchlorodimethylgermane (82546-74-5) + 1,1'-(1,2-ethanediyl)bisbenzene (103-29-7) + dichlorodimethylgermanium (1529-48-2)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In benzene; 120°C for 10 h;

Reference yield: 93.0%

germanium (7440-56-4) + methylene chloride (74-87-3) → chlorotrimethylgermane (1529-47-1) + methyltrichlorogermane (993-10-2) + dichlorodimethylgermanium (1529-48-2)

Guidance literature:

With copper; In neat (no solvent); mixing Ge and Cu, heating this contact mass in a reactor (350°C, 2 h) in a stream of purified N2, raising temp. to 425+/-5°C, replacing N2 by CH3Cl, getting a liq. product after 15 min in the ice-cooled receiver flask, react. time: 14 h; bubbling N2 through the resulting product mixture for 15 min to remove dissolved CH3Cl, detn. by (1)H NMR spectroscopy;

upstream raw materials:

(1R,8S)-3,4,6,11,11-Pentamethyl-1,8,9,10-tetraphenyl-11-germa-tricyclo[6.2.1.0^2,7]undeca-2⁽⁷⁾,3,5,9-tetraene

germanium

methylene chloride

germaniumtetrachloride

Downstream raw materials:

dimethyldiphenylgermane

chloro-trimethyl-silane

1,3-di-tert-butyl-4-chloro-2,2-dimethyl-1,3,2,4-diazagermaboretidine

bis-(2,2'-chloro octafluoro cyclohexenyl-(1,1')) dimethyl germane